A Pharmacodynamic Turnover Model Capturing Asymmetric Circadian Baselines of Body Temperature, Heart Rate and Blood Pressure in Rats: Challenges in Terms of Tolerance and Animal-handling Effects

Author： Sällström Björn   Visser Sandra   Forsberg Tomas   Peletier Lambertus   Ericson Ann-Christine   Gabrielsson Johan  

Publisher： Springer Publishing Company

ISSN： 1567-567X

Source： Journal of Pharmacokinetics and Pharmacodynamics, Vol.32, Iss.5-6, 2005-12, pp. : 835-859

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