Structural-functional model of the mitotic chromosome

Author: Polyakov V.   Zatsepina O.   Kireev I.   Prusov A.   Fais D.   Sheval E.   Koblyakova Yu.   Golyshev S.   Chentsov Yu.  

Publisher: MAIK Nauka/Interperiodica

ISSN: 0006-2979

Source: Biochemistry (Moscow), Vol.71, Iss.1, 2006-01, pp. : 1-9

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Abstract

In the present review the structural role of noncoding DNA, mechanisms of differential staining of mitotic chromosomes, and structural organization of different levels of DNA compactization are discussed. A structural-functional model of the mitotic chromosome is proposed based on the principle of discreteness of structural levels of DNA compactization.