Author: Henderson Wendy Schlenk Elizabeth Kim Kevin Hadigan Colleen Martino Angela Sereika Susan Erlen Judith
Publisher: Routledge Ltd
ISSN: 1360-0451
Source: AIDS Care, Vol.22, Iss.4, 2010-04, pp. : 483-490
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
Background. Management of human immunodeficiency virus (HIV) infection with potent antiretroviral medication has transformed HIV into a chronic condition and has shifted much of the burden of disease to co-morbid conditions such as liver disease (LD). LD alone has been shown to have a significant effect on one's health-related quality of life (HRQOL). Clinical evidence suggests that the growing number of persons living with HIV+LD may have a poorer HRQOL than persons with HIV without LD. To date, the widely accepted instrument to assess HRQOL, Medical Outcomes Study-HIV Health Survey (MOS-HIV), has not been evaluated for reliability and validity in a population of HIV-infected persons with LD. Methods. HRQOL was prospectively assessed using the MOS-HIV in a sample of 532 HIV-infected adults on antiretroviral therapy (n=305 HIV and n=227 HIV+LD). In addition, participants completed standardized questionnaires of sociodemographics and co-morbid conditions. Results. The psychometric properties of the MOS-HIV were supported by testing reliability and construct, convergent, discriminative, and predictive validity. The MOS-HIV discriminated between those persons living with HIV with and without LD on the basis of the physical function subscale scores (p=0.018). Conclusion. This study found the MOS-HIV valid and reliable instrument in persons with HIV+LD.
Related content
By Bekele Tsegaye Rourke Sean B. Tucker Ruthann Greene Saara Sobota Michael Koornstra Jay Monette Laverne Rueda Sergio Bacon Jean Watson James Hwang Stephen W. Dunn James Guenter Dale
AIDS Care, Vol. 25, Iss. 3, 2013-03 ,pp. :
Self-help and life quality in persons with HIV disease
AIDS Care, Vol. 8, Iss. 6, 1996-12 ,pp. :