Extrahepatic Metabolism by CYP2E1 in PBPK Modeling of Lipophilic Volatile Organic Chemicals: Impacts on Metabolic Parameter Estimation and Prediction of Dose Metrics

Author: Yoon Miyoung   Madden Michael C.   Barton Hugh A.  

Publisher: Taylor & Francis Ltd

ISSN: 1087-2620

Source: Journal of Toxicology and Environmental Health, Vol.70, Iss.18, 2007-01, pp. : 1527-1541

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Abstract