The effects of Leptospira serotype pomona in sheep of different haemoglobin types

Author: Hodges RT   Millar KR   Revfeim KJA  

Publisher: Taylor & Francis Ltd

ISSN: 1176-0710

Source: New Zealand Veterinary Journal, Vol.24, Iss.8, 1976-08, pp. : 163-166

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

In the majority of adult sheep there are one or both of two genetically determined haemaglobin types designated Hb-A or Hb-B. The three phenotypes are A, AB or B. These haemoglobin types can be identified by differences in electrophoretic moblility (Harris and Warren, Evans et al 1956). A third haemoglobin type, designated Hb-C, is associated with the Hb-A gene and is produced under conditions resulting in anaemia (Blunt and Evans, 1963). There is slme evidence of a relationship between haemoglobin types and variations in certain physiological characteristics or productive traits (Agar et al 1972). In an earlier study of experimental Leptospira serotype pomona infectioln in sheep it was found that the severity of the resultant haemoglobinuria and anaemia did not appear to be related to the number of leptospirae inoculated (Holdges, 1974). Attempts to produce so-called “typical” clinical manifestations of leptospirosis in farm livestock under experimental conditions are frequently unsuccessful. The object of this investigation was to determine whether sheep of different haemoglobin types varied in their response following inoculation with Leptospira serotype pomona.