Description
Despite years of research world-over, non-toxic and effective radiomodulators remain elusive. In recent years, there has been a shift towards the use of herbals, which are also apparently being viewed as sources of promising radiomodulatory drugs. This book discusses the potential of radiation countermeasure agents and radiosensitizers of herbal origin, their multifaceted mode of action, specifically the use of the former in a nuclear theatre of operations, rescue operations and deep space missions in addition to their application during radiotherapy.
Chapter
SECTION I: Herbals for Radiomodulation (Radioprotection/Radiosensitization): An Overview
1 Radiomodulatory Compounds of Herbal Origin for New Frontiers in Medicine, Homeland Security, Management of Radiological Incidents and Space Applications
SECTION II: Phytomedicine for Radioprotection and Management of Radiation Injuries
2 Indian Medicinal Herbs and Ayurvedic Formulations as Potential Radioprotectors
3. Irradiation, Radioprotection and Nigella sativa
4. Modulation of Radiation-induced Damage by Serbian Natural Plant Products: Implications for Radioprotection
5. Phytoceuticals for Radioprotection with Special Reference to Egyptian Flora
6. Melatonin Mitigates the Damaging Effects of Ionizing Radiation
7. Radioprotective Effect of Citrus and Hawthorn Extracts against Genotoxicty Induced by Gamma Irradiation
8. The Healing Potential of Indigenous Essential Oils from New Zealand in the Prevention and Management of Radiation-induced Mucositis
SECTION III: Biological and Behavioural Radioprotection by Dietary Ingredients/Nutraceuticals
9. Piper betel Leaves: A Potential Gold Mine of Radioprotective and Photoprotective Compounds
10. Dietary Antioxidants and Phytochemicals in Radioprotection and Therapy
11. Effects of Berry Fruits on Neurocognitive Deficits Produced by Exposure to Space Radiation
12. Radioprotection by the Soy Isoflavone Genistein
13. Propolis and Related Flavonoids as Radioprotective Agents
SECTION IV: Elucidation of Mechanism of Action of Herbal Radioprotectors (A Stepping Stone for Designing of Novel Radiomodulators)
14. Radioprotective Effects of Ginkgo biloba via its Antioxidant Action
15. Novel Strategies for Protecting Mitochondria (the Cellular Powerhouse) against Low-LET Radiation: A Review
16. Andrographis paniculata: An Emerging Radioprotective Agent for Membrane Proteins
17. Mitigation of Deleterious Effects of Ionizing Radiation by Phytoceuticals: Mechanistic Studies with Centella asiatica
SECTION V: Cancer Therapy: The Role of Radiosensitizers of Natural Origin
18. The Radiosensitizing Effects of L-Canavanine
19. Withaferin A – A Phytosteroid of Promise for Tumour Sensitization in Cancer Therapy
20. The Radiosensitizer Hypericin as Adjuvant Therapy in the Treatment of Central Nervous System Tumours
21. Radiosensitizing Activity of the Indian Medicinal Plant Tinospora cordifolia Miers ex Hook F & Thoms in Tumour-bearing Mice
SECTION VI: Antioxidants and Radiotherapy: The Enigmatic Connection
22. Do Antioxidants Reduce the Efficacy of Radiotherapy?
Herbal Radiomodulators
：Applications in Medicine, Homeland Defence and Space
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