Fetal Nutrition and Adult Disease :Programming of Chronic Disease through Fetal Exposure to Undernutrition ( Frontiers in Nutritional Science Series. 2 )

Publication subTitle :Programming of Chronic Disease through Fetal Exposure to Undernutrition

Publication series :Frontiers in Nutritional Science Series. 2

Author: Langley-Evans   S.C.  

Publisher: CABI Publishing‎

Publication year: 2004

E-ISBN: 9780851990620

P-ISBN(Hardback):  9780851998213

Subject: R363.1 etiology

Keyword: Dietics and Nutrition

Language: ENG

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Description

Over the last decade epidemiological studies have suggested that the risk of coronary heart disease, stroke mortality and hypertension is, in part, related to the environment encountered during fetal life. In particular, maternal undernutrition during pregnancy has been highlighted as a causal factor in the long-term programming of disease risk.This book, which brings together the perspectives of leading researchers from Europe, the USA and Australasia, provides the reader with a detailed account of the evidence for and against the nutritional programming of human disease, and considers the biological basis of programming. The book addresses a topic of great current interest and consists of three sections: programming the fetus; programming human disease; and the biological basis of nutritional programming.

Chapter

2 Nutritional Basis for the Fetal Origins of Adult Disease

3 Intrauterine Hypoxaemia and Cardiovascular Development

4 Epidemiology of the Fetal Origins of Adult Disease: Cohort Studies of Birthweight and Cardiovascular Disease

5 Early-life Origins of Adult Disease: is There Really an Association Between Birthweight and Chronic Disease Risk?

6 Experimental Models of Hypertension and Cardiovascular Disease

7 Associations between Fetal and Infant Growth and Non-insulin-dependent Diabetes

8 Programming of Diabetes: Experimental Models

9 Birthweight and the Development of Overweight and Obesity

10 Maternal Nutrition in Pregnancy and Adiposity in Offspring

11 Renal Disease and Fetal Undernutrition

12 Perinatal Determinants of Atopic Disease

13 Fetal Programming of Immune Function

14 Programming in the Pre-implantation Embryo

15 Endocrine Responses to Fetal Undernutrition: the Growth Hormone–Insulin-like Growth Factor Axis

16 Impact of Intrauterine Exposure to Glucocorticoids upon Fetal Development and Adult Pathophysiology

Index

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