When Experiments Travel :Clinical Trials and the Global Search for Human Subjects

Publication subTitle :Clinical Trials and the Global Search for Human Subjects

Author: Petryna Adriana;;;  

Publisher: Princeton University Press‎

Publication year: 2009

E-ISBN: 9781400830824

P-ISBN(Paperback): 9780691126562

Subject: C91 Sociology;C912.4 cultural anthropology, social anthropology;R-0 General Theory

Keyword: 一般理论,社会学

Language: ENG

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Description

The phenomenal growth of global pharmaceutical sales and the quest for innovation are driving an unprecedented search for human test subjects, particularly in middle- and low-income countries. Our hope for medical progress increasingly depends on the willingness of the world's poor to participate in clinical drug trials. While these experiments often provide those in need with vital and previously unattainable medical resources, the outsourcing and offshoring of trials also create new problems. In this groundbreaking book, anthropologist Adriana Petryna takes us deep into the clinical trials industry as it brings together players separated by vast economic and cultural differences. Moving between corporate and scientific offices in the United States and research and public health sites in Poland and Brazil, When Experiments Travel documents the complex ways that commercial medical science, with all its benefits and risks, is being integrated into local health systems and emerging drug markets.

Providing a unique perspective on globalized clinical trials, When Experiments Travel raises central questions: Are such trials exploitative or are they social goods? How are experiments controlled and how is drug safety ensured? And do these experiments help or harm public health in the countries where they are conducted? Empirically rich and theoretically innovative, the book shows that neither the language of coercion nor that of rational choice fully captures the range of situations and value systems at work in medical experiments today. When Experiments Travel challenges conventional understandings of the ethics and politics of transnational science and changes the way we think about global medicine and the new infrastructures of our lives.

Chapter

Ethics as “Workable Document”

Floater Sites and Hidden Harms

The Aftermath of Clinical Trials

CHAPTER TWO: ARTS OF DRUG DEVELOPMENT

Study Mills

Drug-Development Services

From Vulnerable to Professional Subjects

The Pharmaceutical Boom and Everyday Research

Engineering Out Harm

The Scientific Plateau and the New Safety Paradigm

CHAPTER THREE: THE GLOBAL CLINICAL TRIAL

How Many Clinical Trials Are Being Carried Out Worldwide?

The Polish Market and the “Nonexistent” Patient

Clinical Research Frontiers

Collaborations in Global Science

Akademia Kliniczna

The Work of Slack

Patient-Consumers

“Our society was not competitive”

Pivotal Countries

Insurance and Legal Protection

CHAPTER FOUR: PHARMACEUTICALS AND THE RIGHT TO HEALTH

Reclaiming Patients and the Evidence Base of Drugs

“Pharmaceuticals are the new gold”

Health Technology Assessment in Brazil

The Judicialization of Health

Alternative Treatment Guidelines

The Clinical Research Unit

When a Country Is a Pharmacy

A Public Health Experiment

What Happens When Clinical Trials End

The Values Patients Bring

Information Asymmetry and Agency

CONCLUSION: THE FUTURE OF GLOBAL MEDICINE

Scientific Evidence and Value

Drugs as Public Goods

Global Health Markets

Innovation

Acknowledgments

Notes

References

Index

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