Psoriasis :Diagnosis and Management

Publication subTitle :Diagnosis and Management

Author: Wolfram Sterry  

Publisher: John Wiley & Sons Inc‎

Publication year: 2014

E-ISBN: 9781118661826

P-ISBN(Hardback):  9780470657362

Subject: R758.63 Psoriasis and parapsoriasis

Keyword: nullnull

Language: ENG

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Description

Practical and user-friendly, this is the ideal guide to the diagnosis and treatment of psoriasis, helping you navigate a logical management pathway through a complex maze of possibilities.

Psoriasis is a cruel disease that can seriously affect the sufferer’s quality and length of life. It is also highly idiosyncratic, with features that vary greatly from patient to patient; this being mirrored in the highly variable response to treatment. It is increasingly recognized that psoriasis is not a discrete disease and that many patients suffer two or three comorbid conditions that can complicate the efforts of doctors treating patients.

Psoriasis: Diagnosis and Management will provide dermatologists of all levels with a practical, well-illustrated approach to fully understanding the disease, including clear, clinical guidance to enable best-practice and effective management of patients.

In full color throughout and excellently illustrated, key highlights include:

  • easily understandable description of the psoriasis pathogenesis;
  • a strong emphasis on the clinical features of psoriasis;
  • careful consideration of comorbid conditions as part of the psoriatic spectrum to be managed;
  • coverage of both traditional and contemporary management approaches;
  • plenty of diagnostic algorithms and management protocols to aid the daily practical care of patients.

Brought to you by several of the world’s leading authorities on the subject, Psoriasis: Diagnosis and Management is an essential purchase for the dermatologist.

Chapter

Part II Etiology and pathogenesis

Chapter 3 Microscopic skin alterations

The human skin: a multilayered, dynamic barrier to the environment

The psoriatic skin: inflammation with epidermal and vascular remodeling

Further reading

Chapter 4 Pathogenesis of psoriasis

Sensitization phase: antigen processing and presentation

Sensitization phase: generation of effector and memory T-cells

Effector phase: infiltration of immune cells into the skin

Effector phase: immune cell activation in the skin

Effector phase: tissue-cell response

Further reading

Chapter 5 Genetics of psoriasis

Further reading

Part III Clinical features/diagnostic procedure

Chapter 6 Plaque psoriasis

Plaque psoriasis

Plaque psoriasis in special localizations

Chapter 7 Gutatte psoriasis

Further reading

Chapter 8 Erythrodermic psoriasis

Further reading

Chapter 9 Pustular psoriasis

Generalized pustular psoriasis (GPP)

Generalized pustular psoriasis of pregnancy (GPPP)/Impetigo herpetiformis (IH)

Annular psoriasis [erythema annulare centrifugum-type (EACP)]

Psoriasis vulgaris with pustulation

Palmoplantar pustular psoriasis (PPP)

Acrodermatitis continua suppurativa (Hallopeau)

Further reading

Chapter 10 Nail psoriasis

Clinical picture and pathophysiology

Diagnostic procedure

Burden of disease

Further reading

Chapter 11 Psoriatic arthritis

Epidemiology

Clinical picture

Clinical classification of PsA

Diagnostic procedures

Laboratory findings

Imaging

Prognosis

Further reading

Chapter 12 Mucosal presentation of psoriasis

Further reading

Chapter 13 Psoriasis in different life situations

Psoriasis in children

Psoriasis in pregnancy

Psoriasis in the elderly

Further reading

Part IV Evaluation of disease severity

Chapter 14 Evaluation of disease severity—clinical scores and questionnaires

Assessment of skin involvement

Assessment of nail psoriasis

Assessment of psoriasis arthritis (PsA)

Spine assessment

Assessment of enthesitis

Assessment of dactylitis

Imaging techniques

Visual analog scale (VAS)

Quality-of-Life (QOL) Questionnaires

Further reading

Appendix

Part V Psoriasis and associated diseases

Chapter 15 Psoriasis and associated diseases

Cardiovascular disease and metabolic syndrome

Obesity

Atherogenic dyslipidemia

Hypertension

Inflammatory bowel disease

Other inflammatory diseases

Psychosocial aspects

Depression

Nicotine use

Alcohol

Conclusion

Further reading

Part VI Therapeutic management

Chapter 16 Therapeutic aim of psoriasis therapy

Further reading

Chapter 17 Treatment of plaque psoriasis

Topical therapy of psoriasis

General principles

Corticosteroid

Vitamin D analogs

Tazarotene

Dithranol (anthralin)

Tar

Calcineurin inhibitors

Comparative efficacy and safety of topical treatments

Management of psoriasis on scalp, face, flexures, palms, soles, and nails

Further reading

Phototherapy and photochemotherapy

History

Requirements for phototherapy and photochemotherapy

Phototherapy

Photochemotherapy

Mechanisms of phototherapy and photochemotherapy

Risks and side-effects of phototherapy and photochemotherapy

Further reading

Classical systemic treatments

When to consider a systemic treatment for your patient

Available systemic treatments

Positioning the systemic treatments

Further reading

Biologics

Topic of interest—ending of biologic names

TNF inhibitors

Ustekinumab (UST)

Alefacept (ALE)

Biologics and concomitant medications

Safety aspects of biologics and monitoring of therapy

Topic of interest—paradoxical skin reactions by TNF inhibitors

Indications—which patients are candidates for therapy with biologics?

Topic of interest: efalizumab

Further reading

Chapter 18 Special therapeutic aspects

Psoriasis capitis

Intertriginous psoriasis

Guttate psoriasis

Erythrodermic psoriasis

Pustular psoriasis

Nail psoriasis

Further reading

Chapter 19 Combination treatments

Why combination treatment of psoriasis?

Beneficial combinations

Contraindicated combinations and combinations for restrictive use

How to use combination treatment in practice

Further reading

Chapter 20 Optimizing adherence to treatment

Further reading

Chapter 21 Psoriasis therapy in children

Topical treatment

UV-light-therapy and systemic treatment

Fumaric acid esters

Further reading

Chapter 22 Therapy of psoriasis during pregnancy

Management of psoriasis in pregnancy

Treatment options during pregnancy

Management of psoriasis postpartum/breastfeeding

Further reading

Chapter 23 Recent and future developments in targeted therapy

Current and emerging biologic therapies

Oral systemic treatments in development

Future topical therapies

Personalized medicine

Conclusion

Further reading

Index

End User License Agreement

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