Description
Practical and user-friendly, this is the ideal guide to the diagnosis and treatment of psoriasis, helping you navigate a logical management pathway through a complex maze of possibilities.
Psoriasis is a cruel disease that can seriously affect the sufferer’s quality and length of life. It is also highly idiosyncratic, with features that vary greatly from patient to patient; this being mirrored in the highly variable response to treatment. It is increasingly recognized that psoriasis is not a discrete disease and that many patients suffer two or three comorbid conditions that can complicate the efforts of doctors treating patients.
Psoriasis: Diagnosis and Management will provide dermatologists of all levels with a practical, well-illustrated approach to fully understanding the disease, including clear, clinical guidance to enable best-practice and effective management of patients.
In full color throughout and excellently illustrated, key highlights include:
- easily understandable description of the psoriasis pathogenesis;
- a strong emphasis on the clinical features of psoriasis;
- careful consideration of comorbid conditions as part of the psoriatic spectrum to be managed;
- coverage of both traditional and contemporary management approaches;
- plenty of diagnostic algorithms and management protocols to aid the daily practical care of patients.
Brought to you by several of the world’s leading authorities on the subject, Psoriasis: Diagnosis and Management is an essential purchase for the dermatologist.
Chapter
Part II Etiology and pathogenesis
Chapter 3 Microscopic skin alterations
The human skin: a multilayered, dynamic barrier to the environment
The psoriatic skin: inflammation with epidermal and vascular remodeling
Chapter 4 Pathogenesis of psoriasis
Sensitization phase: antigen processing and presentation
Sensitization phase: generation of effector and memory T-cells
Effector phase: infiltration of immune cells into the skin
Effector phase: immune cell activation in the skin
Effector phase: tissue-cell response
Chapter 5 Genetics of psoriasis
Part III Clinical features/diagnostic procedure
Chapter 6 Plaque psoriasis
Plaque psoriasis in special localizations
Chapter 7 Gutatte psoriasis
Chapter 8 Erythrodermic psoriasis
Chapter 9 Pustular psoriasis
Generalized pustular psoriasis (GPP)
Generalized pustular psoriasis of pregnancy (GPPP)/Impetigo herpetiformis (IH)
Annular psoriasis [erythema annulare centrifugum-type (EACP)]
Psoriasis vulgaris with pustulation
Palmoplantar pustular psoriasis (PPP)
Acrodermatitis continua suppurativa (Hallopeau)
Chapter 10 Nail psoriasis
Clinical picture and pathophysiology
Chapter 11 Psoriatic arthritis
Clinical classification of PsA
Chapter 12 Mucosal presentation of psoriasis
Chapter 13 Psoriasis in different life situations
Part IV Evaluation of disease severity
Chapter 14 Evaluation of disease severity—clinical scores and questionnaires
Assessment of skin involvement
Assessment of nail psoriasis
Assessment of psoriasis arthritis (PsA)
Visual analog scale (VAS)
Quality-of-Life (QOL) Questionnaires
Part V Psoriasis and associated diseases
Chapter 15 Psoriasis and associated diseases
Cardiovascular disease and metabolic syndrome
Inflammatory bowel disease
Other inflammatory diseases
Part VI Therapeutic management
Chapter 16 Therapeutic aim of psoriasis therapy
Chapter 17 Treatment of plaque psoriasis
Topical therapy of psoriasis
Comparative efficacy and safety of topical treatments
Management of psoriasis on scalp, face, flexures, palms, soles, and nails
Phototherapy and photochemotherapy
Requirements for phototherapy and photochemotherapy
Mechanisms of phototherapy and photochemotherapy
Risks and side-effects of phototherapy and photochemotherapy
Classical systemic treatments
When to consider a systemic treatment for your patient
Available systemic treatments
Positioning the systemic treatments
Topic of interest—ending of biologic names
Biologics and concomitant medications
Safety aspects of biologics and monitoring of therapy
Topic of interest—paradoxical skin reactions by TNF inhibitors
Indications—which patients are candidates for therapy with biologics?
Topic of interest: efalizumab
Chapter 18 Special therapeutic aspects
Chapter 19 Combination treatments
Why combination treatment of psoriasis?
Contraindicated combinations and combinations for restrictive use
How to use combination treatment in practice
Chapter 20 Optimizing adherence to treatment
Chapter 21 Psoriasis therapy in children
UV-light-therapy and systemic treatment
Chapter 22 Therapy of psoriasis during pregnancy
Management of psoriasis in pregnancy
Treatment options during pregnancy
Management of psoriasis postpartum/breastfeeding
Chapter 23 Recent and future developments in targeted therapy
Current and emerging biologic therapies
Oral systemic treatments in development
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