Clinical Respiratory Physiology

Author： Harris Luke

Publisher： Elsevier Science‎

Publication year： 2013

E-ISBN: 9781483183404

P-ISBN(Paperback): 9780723603740

P-ISBN(Hardback): 9780723603740

Subject： R332 respiratory physiology

Language： ENG

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Description

Clinical Respiratory Physiology covers the practical aspects and theoretical concepts of applied respiratory physiology. The book describes the methods of measuring ventilator capacity, lung volumes, ventilation, diffusion, cardiac output, and ventilation-perfusion rates. The text also tackles methods of measuring airway resistance and blood gases. Compliance and work of breathing, acid-base regulation, and tests of cardiorespiratory function during exercise are also looked into. Junior doctors working in respiratory units, technicians in respiratory laboratories, general physicians, and senior medical students will find the book useful.

Chapter

Front Cover

Clinical Respiratory Physiology

Table of Contents

PREFACE

Dedication

SYMBOLS AND ABBREVIATIONS

Chapter One. Ventilatory Capacity (Timed Spirometry)

Expiratory Measurements

Inspiratory Measurements

Predicted values for FEV based on Age, Height and Sex

Chapter Two. Lung Volumes

Closed Circuit Helium Dilution Method for FRC

Open Circuit Nitrogen Washout Method

Whole-body Plethysmography Method

Total Lung Capacity based on Height for Males and Height and Age for Females

Residual Volume as Percentage of Total Lung Capacity

Chapter Three. Ventilation

Illustration of Inter-relationship between VE, VD and VA

Chapter Four. Oxygen Consumption and Carbon Dioxide Output

Chapter Five. Diffusion

Steady State Methods

Single Breath Method

Rebreathing Method

Diffusion Coefficient (kCO)

Transfer Factor (TL) based on Age and Height

Chapter Six. Cardiac Output (Pulmonary Blood Flow)

Direct Fick O2 Method

Indirect Fick CO2 Method

Body Plethysmograph Method

Dye Dilution Method

Chapter Seven. Ventilation—Perfusion Ratios

Radioactive Xenon Method

Anatomical Shunt (Oxygen test)

Physiological Shunt and Venous Admixture Effect

Physiological Dead Space

Single Breath CO2 Test

Alveolar-arterial O2 Difference (A – aDO2)

Arterio-alveolar CO2 Difference (a — ADCO2)

Diagrammatic Representation of Effects of Changes in Ventilation-perfusion Ratios

Chapter Eight. Compliance and Work of Breathing

Work of Breathing

Respiratory Frequency and Work of Breathing

Chapter Nine. Airway Resistance

Airway Conductance

Chapter Ten. Blood Gases

Normal Values (at Rest)

Rebreathing Method for PVCO2

CO2 dissociation curve for whole blood between PCO2 40 and PCOa 60

HbO2 dissociation curve (PH7.4, temp. 37°C

The Inter-relationship between O2 and CO2

Chapter Eleven. Acid-base Regulation

Primary CO2 Retention (Respiratory Acidaemia)

Primary CO2 Depletion (Respiratory Alkalaemia)

Metabolic Acidaemia

Metabolic Alkalaemia

Mixed Disturbances

Summary

Chapter Twelve. Exercise Studies

Appendix One: Patterns of Disturbed Function

Appendix Two: Temperature and Pressure Corrections

BIBLIOGRAPHY

INDEX

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