Neuropharmacology :Studies of Narcotic Drugs

Publication subTitle :Studies of Narcotic Drugs

Author: Bradley   P. B.;Costa   E.  

Publisher: Elsevier Science‎

Publication year: 2014

E-ISBN: 9781483140001

P-ISBN(Paperback): 9780080205656

P-ISBN(Hardback):  9780080205656

Subject: R971 nervous system medication

Language: ENG

Access to resources Favorite

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Description

Neuropharmacology is a collection of papers presented at a symposium of the XXVI International Congress of Physiological Sciences, held in New Delhi, India in 1974. Contributors focus on the neurochemical action of central analgesics and their biochemistry, particularly Viminol R2 and azidomorphine, based on evidence derived using neurohistochemical techniques.
This text is comprised of six chapters; the first of which deals with cholinergic mechanisms in narcotic analgesics. This topic is followed by a discussion on the research on the effects of drugs such as morphine on the central nervous system using amine fluorescence histochemistry; the effect of dextromoramide and methadone on dopamine metabolism in comparison with haloperidol and amphetamine; and the use of pharmacological models to predict opiate dependence. A chapter is devoted to a pharmacological study of the in vivo increase in the cyclic AMP content of rat striatum and nucleus accumbens due to the action of amphetamine, apomorphine, opiates, and antipsychotic drugs, along with the effect of this change on dopamine receptors.
This book will appeal to scientists representing all the major areas of pharmacology, including clinical pharmacology and toxicology, as well as to internists, psychiatrists, neurologists, and anesthesiologists.

Chapter

CHAPTER 1. CHOLINERGIC MECHANISMS IN NARCOTICANALGESICS

REFERENCES

CHAPTER 2. THE USE OF AMINE FLUORESCENCEHISTOCHEMISTRY IN THE STUDY OF DRUGS,ESPECIALLY MORPHINE, ON THE CNS

REFERENCES

CHAPTER 3. EFFECT OF METHADONE AND DEXTROMORAMIDEON DOPAMINE METABOLISM: COMPARISON WITHHALOPERIDOL AND AMPHETAMINE

EFFECT ON ADENYLATE CYCLASE

CONCLUSIONS

REFERENCES

CHAPTER 4. PREDICTIVE VALUES OF PHARMACOLOGICALMODELS TO STUDY OPIATE DEPENDENCE

REFERENCES

CHAPTER 5. ACTION OF OPIATES, ANTIPSYCHOTICS,AMPHETAMINE AND APOMORPHINE ON DOPAMINERECEPTORS IN RAT STRIATUM: IN VIVO CHANGES OF3,5-CYCLIC AMP CONTENT AND ACETYLCHOLINETURNOVER RATE

INTRODUCTION

EXPERIMENTAL STUDIES

REFERENCES

CHAPTER 6. STRUCTURAL FEATURES ASSOCIATED WITHNARCOTICS AND NARCOTIC ANTAGONISTS

REFERENCES

The users who browse this book also browse