Allergy and Tissue Metabolism

Author: Smith   W. G.  

Publisher: Elsevier Science‎

Publication year: 2013

E-ISBN: 9781483225388

P-ISBN(Paperback): 9781483200354

P-ISBN(Hardback):  9781483200354

Subject: Q11 biological evolution and development

Language: ENG

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Description

Allergy and Tissue Metabolism covers some of the more important features of the state of knowledge in the relevant areas of allergy and tissue metabolism.
This book is composed of nine chapters, and starts with a survey of the link between immune system and allergic diseases. The subsequent chapters deal with the evaluation of anaphylactic shock mechanisms using some animal models and the relationship between eosinophils and anaphylaxis. These topics are followed by discussions on the role of histamine, bradykinin, and serotonin in allergy. A chapter examines the slow reacting substance of anaphylaxis. The final chapters consider the therapeutic management of allergic diseases.
This book is of value to allergists, allergologists, immunologists, and researchers and workers in the allied fields.

Chapter

Foreword

Chapter 1. The immunological basis of allergic disease

Anaphylactic shock in animals

Allergy in humans

The effects of antigen–antibody reactions in hypersensitive tissue

Chapter 2. Anaphylactic shock in experimental animals

Anaphylaxis in the dog

Anaphylaxis in the rabbit

Anaphylaxis in the guinea pig

Anaphylaxis in the rat

Anaphylaxis in the mouse

The chemical mediation of anaphylaxis

Chapter 3. The connective tissue mast cells and blood eosinophils

The morphology and distribution of mast cells

The release of histamine from mast cell granules

Tissue response to injury

The role of mast cells in anaphylaxis

Eosinophils

Chapter 4. Histamine

Histamine release by peptone

Histamine release by trypsin

Histamine release by snake venoms

Histamine release by compounds of simple chemical structure

Proteolytic and lecithinase theories of histamine release in anaphylaxis

Chapter 5. The slow reacting substance of anaphylaxis

Early studies of slow reacting substance

Recent studies of slow reacting substance

Chapter 6. Bradykinin

Structure and formation

Pharmacological activity

Chapter 7. Serotonin

Distribution, metabolism and pharmacology

Role of serotonin in anaphylaxis

Chapter 8. Anaphylaxis and intermediary metabolism

Chapter 9.The therapeutic control of allergic disease

References

Index

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