Description
Mechanisms and Regulation of Carbohydrate Transport in Bacteria reviews the developments in the study of the mechanisms and regulation of carbohydrate transport in prokaryotic organisms.
The book presents the progress made in the understanding of transport and regulation of carbohydrates in bacteria in the molecular level. Aspects on the important structural and topographical features of several sugar permeases in Escherichia coli are elucidated; the energy-coupling processes are clearly delineated for most (but not all) types of bacterial carbohydrate permease systems; and mechanistic details of the translocation processes are proposed.
Molecular biologists, microbial biochemists, and cell biologists will find the book a good source of information.
Chapter
Chapter 2. Mechanisms of Carbohydrate
Transport
A. GLYCEROL PERMEASE: FACILITATED DIFFUSION
B. LACTOSE PERMEASE: SUGAR:H+ SYMPORT
C. MELIBIOSE PERMEASE: SUGAR : Na+ SYMPORT
D. MALTOSE PERMEASE: PRIMARY ACTIVE TRANSPORT
Chapter 3. Group Translocation Catalyzed by the Phosphoenolpyruvate : Sugar Phosphotransferase System
A. GENERAL FEATURES OF THE PHOSPHOTRANSFERASE SYSTEM
B. BIOCHEMICAL AND GENETIC NOMENCLATURE OF THE PTS
C. PROPERTIES AND MECHANISM OF ACTION OF
ENZYME I
E. PROPERTIES AND MECHANISM OF ACTION OF
ENZYME llmtl
F. EVOLUTION OF THE PHOSPHOTRANSFERASE SYSTEM
Chapter 4. Mechanisms of Inducer Exclusion
A. REGULATION OF TRANSPORT BY THE MEMBRANE POTENTIAL
B. REGULATION OF TRANSPORT BY INTRACELLULAR
SUGAR PHOSPHATES
C. PTS-MEDIATED REGULATION OF CARBOHYDRATE
UPTAKE
D. REGULATION OF PTS-MEDIATED CARBOHYDRATE
UPTAKE BY COMPETITION FOR PHOSPHO-HPr
Chapter 5. Mechanisms of Adenylate
Cyclase Regulation in Gram-Negative Bacteria
A. REGULATION OF ADENYLATE CYCLASE BY THE
MEMBRANE POTENTIAL
B. REGULATION BY INTRACELLULAR SUGARP HOSPHATES
C. PTS-MEDIATED REGULATION OF ADENYLATE
CYCLASE
Chapter 6. Involvement of Protein Kinases in the Regulation of Carbohydrate Transport and
Metabolism
A. FUTILE
CYCLES OF SUGAR UPTAKE AND EFFLUX IN
B. PHYSIOLOGICAL CHARACTERIZATION OF INDUCER
EXPULSION
C. HPr KINASE
AND HPr(ser)P PHOSPHATASE IN
D. PROPERTIES OF BACTERIAL PROTEIN KINASES
IN
E. ISOCITRATE DEHYDROGENASE PHOSPHORYLATION
AND THE REGULATION OF CARBON METABOLISM
F. EVOLUTION OF CYCLIC AMP AND PROTEIN KINASES AS REGULATORY AGENTS FOR THE
CONTROL OF CARBON AND ENERGY METABOLISM
Chapter 7. Exogenous Induction of Certain Carbohydrate
Permeases in Bacteria
A. EXOGENOUS INDUCTION OF THE HEXOSE
PHOSPHATE AND PHOSPHOGLYCERATE PERMEASES
B. AUTOGENOUS INDUCTION OF THE PROTEINS
OF THE PHOSPHOTRANSFERASE SYSTEM
C. POSSIBLE INVOLVEMENT OF TRANSPORT PROTEINS
IN TRANSCRIPTIONAL REGULATION
Chapter 8. Permease Classification and Mechanisms: Conclusions and
Future Perspectives
A. DIVERSITY OF PERMEASE MECHANISMS IN LIVING
CELLS
B. CLASSIFICATION OF
CARBOHYDRATE TRANSPORT SYSTEMS IN