Molecules, Cells, and Parasites in Immunology

Author： Larralde   Carlos;Willms   Kaethe;Ortiz-Ortiz   Librado  

Publisher： Elsevier Science‎

Publication year： 2014

E-ISBN: 9781483270265

P-ISBN(Paperback): 9780124368408

P-ISBN(Hardback):  9780124368408

Subject： Q939.91 immunology

Language： ENG

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Description

Molecules, Cells, and Parasites in Immunology contains the proceedings of a symposium on immunology held in Mexico City in the fall of 1979 under the auspices of the National University of Mexico (UNAM). This volume brings together prominent foreign scientists and Mexican investigators to discuss the areas of immunology that being developed at UNAM.
Either in the form of reviews or of original presentations, the various authors proffer observations and ideas that generally relate to the regulation of the immune response at the molecular and cellular levels. The topic of Molecules encompasses the effect of molecular aggregation upon the triggering of physiological events, cooperative binding, and the expression of immunoglobulins during the lymphocyte differentiation process. Under the heading of Cells, there are contributions dealing with the physiological and pathological roles of interiorized antibodies; the mechanisms of antigen recognition by T cells; and the synthesis of membrane proteins by myeloma cells which somehow protect them from killer T cells. The section on Parasites includes some unique contributions on the immunology of human and animal cysticercosis and amebiasis, complemented by a general discussion of host-parasite relationships.

Chapter

Front Cover

Molecules, Cells, and Parasites in Immunology

Copyright Page

Table of Contents

CONTRIBUTORS

PREFACE

ACKNOWLEDGMENTS

CHAPTER 1. MOLECULAR MECHANISMS OF ANTIBODY ACTION: USE OF CROSS-LINKING REAGENTS

I. INTRODUCTION

II. NEW STUDIES

III. CONCLUDING STATEMENT

REFERENCES

CHAPTER 2. MEMBRANE-RECEPTOR MECHANISMS IN ANAPHYLAXIS

I. THE CONCEPT OF A RECEPTOR

II. EXCITABLE TISSUE ANAPHYLAXIS

III. CONNECTIVE TISSUE INVOLVEMENT

IV. TWO DISTINCT RECEPTOR COMPONENTS

ACKNOWLEDGMENTS

REFERENCES

CHAPTER 3. COOPERATIVITY AND ANTIBODY FUNCTION

I. INTRODUCTION

II. EXPERIMENTAL RESULTS

III. COOPERATIVITY OR ARTIFACT?

IV. ESTIMATION OF THE PARAMETERS OF COOPERATIVITY

V. PREVIOUS OBSERVATIONS

VI. DISCUSSION

VII. CONCLUDING REMARKS

ACKNOWLEDGMENTS

REFERENCES

CHAPTER 4. DIFFERENTIATION OF THE B-LYMPHOCYTE

I. INTRODUCTION

II. GENERATION OF B-LYMPHOCYTES

III. THE PRE-B CELL

IV. THE IMMATURE B-CELL

V. DEVELOPMENT OF HEAVY CHAIN CLASS (ISOTYPE) HETEROGENEITY

VI. THE PROBLEM OF MULTIPLE CLASS REPRESENTATION

VII. THE ROLE OF IgD

VIII. MODE OF MEMBRANE INSERTION OF SURFACE IMMUNOGLOBULIN

ACKNOWLEDGMENT

REFERENCES

CHAPTER 5. ANTIBODY PENETRATION INTO LIVING CELLS: MECHANISMS AND CONSEQUENCES

I. INTRODUCTION

II. ANTIBODY PENETRATION AND THE Fc RECEPTOR

III. EVIDENCE OF ANTIBODY PENETRATION IN VIVO

IV. CONSEQUENCES OF ANTIBODY PENETRATION

V. ROLE OF ANTIBODY PENETRATION IN IMMUNOBIOLOGY

ACKNOWLEDGMENT

REFERENCES

CHAPTER 6. LAMBDA LIGHT CHAINS AND IDIOTYPE-BEARING T CELLS

I. INTRODUCTION

II. λ LIGHT CHAINS

III. Id+ ANTI-NP T CELLS

IV. DEPENDENCE OF THE SPECIFICITY OF ANTI-Id ANTIBODIES ON VL DOMAINS OF THE Id-BEARING MOLECULE

V. LOGISTICS

REFERENCES

CHAPTER 7. CELLULAR RECOGNITION IN TUMOR IMMUNOLOGY: TUMOR RESISTANCE TO IMMUNE DESTRUCTION BY CYTOTOXIC T LYMPHOCYTES

I. INTRODUCTION

II. MATERIALS AND METHODS

III. RESULTS

IV. DISCUSSION

REFERENCES

CHAPTER 8. CHEMOTAXIS

I. INTRODUCTION

II. CHEMOTAXIS: GENERAL AND TECHNICAL CONSIDERATIONS

III. CHEMOTAXIS IN HUMAN NEWBORNS AND AMEBIASIS

REFERENCES

CHAPTER 9. BIOCHEMICAL CHARACTERIZATION OF LYMPHOCYTE MEDIATOR-MACROPHAGE INTERACTIONS

I. INTRODUCTION

II. RESULTS AND DISCUSSION

REFERENCES

CHAPTER 10. B LYMPHOCYTE STIMULATION BY PARASITIC ORGANISMS

I. INTRODUCTION

II. METHODS

III. RESULTS

IV. DISCUSSION

ACKNOWLEDGMENT

REFERENCES

CHAPTER 11. THE IMMUNOLOGY OF HUMAN CYSTICERCOSIS

I. INTRODUCTION

II. IMMUNODIAGNOSIS OF BRAIN CYSTICERCOSIS

III. SEROEPIDEMIOLOGY

IV. HUMORAL IMMUNE RESPONSE

V. IMMUNITY TO CYSTICERCOSIS

VI. CELLULAR IMMUNE RESPONSE

VII. HOST-PARASITE INTERFACE

VIII. CONCLUSIONS

REFERENCES

CHAPTER 12. IMMUNOPATHOLOGY OF CYSTICERCOSIS

I. HOST-PARASITE SPECIFICITY

II. ULTRASTRUCTURE OF THE PARASITE SURFACE

IIII. SYNTHESIS OF PARASITE PROTEINS

IV. HOST RESPONSE

ACKNOWLEDGMENTS

REFERENCES

CHAPTER 13. IMMUNOLOGY OF AMEBIASIS

I. INTRODUCTION

II. HUMORAL IMMUNE REACTIONS

III. CELLULAR IMMUNE REACTIONS

IV. IMMUNITY AND ANTIAMEBIC IMMUNIZATION

REFERENCES

CHAPTER 14. THE HOST-PARASITE INTERACTION

I. INTRODUCTION

II. SUSCEPTIBILITY TO INFECTION

III. IMMUNOSUPPRESSION AND IMMUNOPOTENTIATION

IV. ANTIGENS

V. CONCLUSIONS

REFERENCES

CHAPTER 15. THE ROLE OF CIRCUMSTANCE IN IMMUNITY

I. INTRODUCTION

II. CIRCUMSTANCE AND IMMUNITY AT THE LEVEL OF A COMMUNITY

III. CIRCUMSTANCE AND IMMUNITY AT THE LEVEL OF AN ORGANISM

IV. CIRCUMSTANCE AT THE CELLULAR LEVEL

V. CIRCUMSTANCE AT THE MOLECULAR LEVEL

VI. DISCUSSION

REFERENCES

CHAPTREC 16. HEMICAL SYNTHESIS FOR THE UNDERSTANDING OF IMMUNE RESPONSE PHENOMENA AND FOR THEIR MEDICAL APPLICATION

I. INTRODUCTION

II. SYNTHETIC ANTIGENS WITH PEPTIDE DETERMINANTS OF DEFINED SEQUENCE

III. SYNTHETIC PEPTIDE OF CARCINOEMBRYONIC ANTIGEN OF THE COLON

IV. SUPPRESSION OF EAE AND POSSIBLY OF MULTIPLE SCLEROSIS WITH A BASIC SYNTHETIC COPOLYMER

V. ANTIVIRAL EFFECT ON MS-2 COLIPHAGE OBTAINED WITH A SYNTHETIC ANTIGEN

VI. CHALLENGE OF THE COMBINED USE OF SYNTHETIC ANTIGENS AND SYNTHETIC ADJUVANTS

VII. CONCLUDING REMARKS

REFERENCES

INDEX

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