Immunodermatology

Author: Macdonald   D. M.  

Publisher: Elsevier Science‎

Publication year: 2014

E-ISBN: 9781483192000

P-ISBN(Paperback): 9780407003385

P-ISBN(Hardback):  9780407003385

Subject: R751 皮肤病学

Language: ENG

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Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Description

Immunodermatology presents a comprehensive examination of the proceedings that resulted from the International Immunodermatology Symposium which happened in London. It discusses the relationship of immuno-histochemical study to skin disease. It addresses the function and recognition of lymphocytes.
Some of the topics covered in the book are the immunological observations in 12 cases of Kaposi’s herpetic eruption; anti-inflammatory effects of adrenoceptor agonists in patients with atopic eczema; a study of the sensitivity and specificity of cutaneous vascular immunofluorescence; and functional activity of granulocytes from patients with neutrophilic dermatoses. The mechanisms of cutaneous lupus erythematosus are fully covered. An in-depth account of the cytochemical and immunological findings in cutaneous multilobated cell lymphoma are provided. The immunohistological analysis of dermal leprous granulomas is completely presented. A chapter is devoted to the study of human epidermal cell differentiation using monoclonal antibodies. Another section focuses on the prognostic significance of melanoma-associated antigens in primary and metastatic melanomas.
The book can provide useful information to doctors, dermatologists, students, and researchers.

Chapter

Part I: Eczema

Chapter 1. Kaposi's herpetic eruption: immunological observations in 12 cases

Introduction

Materials and methods

Results

Comment

References

Chapter 2. Anti-inflammatory effects of adrenoceptor agonists in patients with atopic eczema

Introduction

Subjects and methods

Results

Discussion

References

Chapter 3. Specific hyposensitization and non-specific immunotherapy in severe atopic dermatitis

Hyposensitization

Non-specific immunotherapy

Transfer factor

Comments

References

Chapter 4. Inhalant and food allergens in atopic eczema assessed by RAST studies

Patients

Materials and methods

Results

Discussion

References

Chapter 5. Analysis of the IgE response to pure cows' milk and hens' egg proteins in eczematous patients

Introduction

Subjects studied

Materials and methods

Results

Discussion

References

Chapter 6. Abnormal intestinal permeability to lactulose in patients with atopic dermatitis

Introduction

Patients and methods

Results

Discussion

References

Chapter 7. Comparison of predictive drug photosensitivity models in guinea pigs, mice and humans

General review

Induction techniques in guinea pigs

Induction techniques in mice

Induction techniques in humans

References

Chapter 8. Actinie reticuloid: sensitivity to light and fragrances

Case report

References

Chapter 9. Cellular events in human skin after challenge with dinitrochlorobenzene

Introduction

Methods

Results

Discussion

Acknowledgements

References

Chapter 10. Inhibition of the suppressor cell circuit of contact allergy by interferon

Methods

Results

Discussion

References

Chapter 11. Lymphocyte transformation test in allergie contact dermatitis by mercury

Materials and methods

Results

Discussion

References

Part II: Labelled antibody studies

Chapter 12. Quantitative analysis of HLA-DR antigen expression by normal human epidermal cells (light microscopy and flow cytometry sorting)

Introduction

Materials and methods

Results

Discussion

References

Chapter 13. Studies of human epidermal cell differentiation using monoclonal antibodies

Introduction

Materials and methods

Results

Discussion

References

Chapter 14. Epidermal B2M labelling in verrucous carcinoma, viral warts and pseudoepitheliomatous hyperplasia

Introduction

Materials and methods

Antisera

Results

Discussion

References

Chapter 15. Epithelial markers in primary skin cancer. An immunoperoxidase study

Introduction

Methods

Controls

Results

Discussion

Acknowledgements

References

Chapter 16. Carcinoembryonic antigen in mammary and extramammary Paget's disease

Introduction

Patients and methods

Results

Discussion

References

Chapter 17. S-100 protein: an immunohistochemical study of fetal eccrine sweat glands and of sweat gland adenomas

Materials and methods

Results

Discussion

References

Chapter 18. Prognostic significance of melanoma-associated antigens in primary and metastatic melanomas

Results and discussion

Acknowledgements

References

Chapter 19. Fcγ-receptors in normal and lesional skin

Materials and methods

Results

Discussion

References

Chapter 20. Immunohistochemical localization of factor VIII related antigen in Kaposi's sarcoma

Patients and methods

Results

Discussion

References

Chapter 21. Ulex europeus 1 : a tool to study vascular endothelium

Introduction

Material and methods

Results

Discussion

References

Chapter 22. NK-cells and nervous tissue share a common antigen

References

Chapter 23. Immunocytochemistry at the electron microscopic level: a new routine technique

Methods

Results

Discussion

References

Part III: Immunocompetent cells: function and recognition

Chapter 24. The IEM techniques in immunodermatology

Introduction

Materials and methods

Results and discussion

References

Chapter 25. Identification and functions of human Langerhans and epidermal indeterminate cells participating in the in vitro generation of alloreactive human cytotoxic T cells

Material and methods

Results

Discussion

Acknowledgements

References

Chapter 26. Human Langerhans cells in in vitro systems: epidermal cell culture, skin explants and skin grafts onto 'nude' mice

Materials and methods

Results

Discussion

References

Chapter 27. Ultrastructural and quantitative evaluation of HLA-DR antigen densities of Langerhans cells (LC) and indeterminate cells (IC) using immunogold labelling

Introduction

Material and methods

Results

Discussion

Acknowledgements

References

Chapter 28. A novel cell population within mouse epidermis

Acknowledgements

References

Chapter 29. S22 antibody: a new marker for mononuclear phagocytes in dermatopathology

Introduction

Materials and methods

Results

Discussion

References

Chapter 30. Heterogeneity of Sézary cells. Multiparameter approach in two cases

Materials and methods

Results and comment

References

Chapter 31. Longitudinal study of surface antigen pattern in cutaneous T-cell lymphomas

References

Chapter 32. Cytochemical and immunological findings in cutaneous multilobated cell lymphoma

Materials and methods

Results and comment

References

Chapter 33. Lymphomatoid papulosis: its relationship with mycosis fungoides and Hodgkin's disease

Introduction

Lymphomatoid papulosis and Hodgkin's disease

Lymphomatoid papulosis and mycosis fungoides

Pathogenetic mechanisms in mycosis fungoides, Hodgkin's disease and lymphomatoid papulosis: a unifying concept

References

Chapter 34. Morphological recognition of 'immunoblastomas' and 'centroblastomas'

References

Chapter 35. Natural killer cells in skin pathology

Introduction

Materials and methods

Results

Discussion

References

Chapter 36. Influence of lymphocytes from patients with systemic sclerosis on cultured fibroblasts

Method

Results

Discussion

Acknowledgements

References

Chapter 37. Erythema fixum: a histological and an immunoperoxidase study using monoclonal antibodies

Patients and methods

Results

Discussion

References

Chapter 38. Immunohistological analysis of dermal leprous granulomas

Patients

Methods

Results and discussion

Conclusion

Acknowledgements

References

Chapter 39. A quantitative labelled antibody study of the evolving patterns of T cell subsets in lichen planus

Introduction

Materials and methods

Results

Discussion

References

Chapter 40. Plasma cells accumulating around epidermal neoplasias. Immunoenzymatic staining of paraffin sections

Introduction

Materials and method

Results

Discussion

References

Chapter 41. Immunoglobulin demonstration in circumorificial plasmacytosis

Material and Methods

Results

Discussion

References

Chapter 42. Immunocytochemical and electron microscopic observations of Langerhans cells in psoriasis before and during etretinate therapy

Introduction

Materials and methods

Results

Discussion

References

Chapter 43. Epidermal T lymphocytes and HLA-DR expression in psoriasis

Introduction

Methods

Results

Discussion

Reference

Chapter 44. The significance of antigen presenting cells in psoriasis

Introduction

Materials and methods

Results

Discussion

References

Chapter 45. Stimulation of T lymphocytes by isolated autologous or allogeneic human epidermal cells

Introduction

Materials and methods

Results

Discussion

References

Chapter 46. Production of lipoxygenase products of arachidonic acid by isolated human epidermal cells

Introduction

Materials and methods

Results

Discussion

Acknowledgements

References

Chapter 47. Morphological changes in polymorphonuclear leucocytes (PMN) with and without chemotaxic stimulation are modulated by ferritin-labelled lectins

References

Chapter 48. Modulation of polymorphonuclear leucocyte (PMN) chemotaxis and Superoxide anion production by wheat germ agglutinin (WGA) in skin diseases with PMN hyper-responsiveness

Reference

Chapter 49. Study of microphage functions in lichen ruber planus

References

Chapter 50. Functional activity of granulocytes from patients with neutrophilic dermatoses

References

Part IV: Vasculitis and autoimmune disease

Chapter 51. Role of platelet activating factor (Paf-acether) in the pathogenesis of vasculitis

Introduction

Subjects and methods

Results

Discussion

References

Chapter 52. Cutaneous vascular immunofluorescence: a sensitivity and specificity study

Methods

Results

Discussion

Conclusion

References

Chapter 53. Immuno-and histopathology of the skin in patients with rheumatoid arthritis

Introduction

Materials and methods

Results

Discussion

Acknowledgements

References

Chapter 54. Circulating immune complexes containing IgG anti-gliadin antibody in dermatitis herpetiformis detected by sucrose density gradient centrifugation and subsequent serological analysis

Introduction

Patients and Sera

Methods

Results

Discussion

References

Chapter 55. Microfibrils of elastic fibres as a major site of IgA deposition in dermatitis herpetiformis: an immunofluorescence and immunoelectron microscopical study

Introduction

Materials and methods

Results

Discussion

Acknowledgements

References

Chapter 56. Mixed immunodermatological characteristics of pemphigoid and dermatitis herpetiformis

Introduction

Case presentation

Comments

References

Chapter 57. The spectrum of linear IgA dermatoses

Chronic bullous disease of childhood

Linear IgA disease of adults

Transitional cases (chronic bullous disease of childhood to linear IgA disease of adults)

Childhood cicatricial pemphigoid with linear IgA deposits

Cicatricial pemphigoid

Discussion

References

Chapter 58. Paternal responsibility for herpes gestationis

Introduction

The effect of a change in sexual consort

Herpes gestationis and trophoblastic tumours

HLA findigs

Spared pregnancies

Discussion

References

Chapter 59. Suppressor cell functions in pemphigus patients

References

Chapter 60. Radioimmunoassay to study pemphigus antibodies

References

Chapter 61. T-cell subsets and Langerhans cells in cutaneous lupus erythematosus

Introduction

Patients

Methods

Results

Discussion

Acknowledgements

References

Chapter 62. New evidence pertaining to the mechanism of cutaneous lupus erythematosus

Chapter 63. Serological profiles as immunological markers for different clinical presentations of lupus erythematosus and scleroderma

Materials and methods

Results

Discussion

Acknowledgements

References

Chapter 64. Antibodies to nuclear organelles occur in scleroderma and relate to clinical pattern

Introduction

Methods

Results

Discussion

References

Chapter 65. Treatment of alopecia areata with diphencyprone induces hair regrowth and affects the composition of peribulbar infiltrates

Induction of hair regrowth by diphencyprone

Influence of diphencyprone on the peribulbar infiltrate

OKT4/OKT8 ratio in the peribulbar infiltrates of untreated alopecia areata

OKT4/OKT8 ratio in the peribulbar infiltrates of alopecia areata treated with diphencyprone

Demonstration of OKT6 positive cells in the peribulbar infiltrates of treated and untreated alopecia areata

Discussion

Acknowledgement

References

Chapter 66. Immunopathology of bowel bypass disease

References

Chapter 67. Does IgM class rheumatoid factor disturb Candida specific IgM-diagnosis

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