Chapter
Part 1: Aminopyridines and Ionic Currents in Excitable Membranes
Chapter 1. General Review on Potassium Currents in Excitable Membranes of Nerve and Muscle
TIME COURSE OF POTASSIUM CURRENTS
DIAMETER AND CONDUCTANCE OF SINGLE POTASSIUM CHANNELS
PECULIARITIES OF THE Κ PERMEABILITY IN CERTAIN TISSUES
Chapter 2. Effects of Aminopyridines on Potassium Currents of the Nodal Membrane
Chapter 3. Properties and Physiological Roles of Κ +
Currents in Frog Myelinated Nerve Fibres as
Revealed by 4-Amino Pyridine
Chapter 4. Effects of Aminopyridines on Ionic Currents and Ionic Channel Noise in Unmyelinated Axons
Chapter 5. 3- and 4-Aminopyridine in Synaptic Transmission at the Squid Giant Synapse
Part 2: Aminopyridines and Synaptic Transmission
Chapter 6. General Principles of Synaptic Transmission
Chapter 7. Effects of Aminopyridines on Neuromuscular Transmission
AMINOPYRIDINES ON VERTEBRATE NEUROMUSCULAR JUNCTIONS
AMINOPYRIDINES ON INVERTEBRATE NEUROMUSCULAR JUNCTIONS
Chapter 8. Effects of 4-Aminopyridine on Transmission in Excitatory and Inhibitory Synapses in the Spinal Cord
DOSAGE AND TIME COURSE OF EFFECTS OF 4-AP
EFFECTS OF 4-AP ON INHIBITORY PATHWAYS
CONTROL TESTS ON THE SITE OF ACTION OF 4-AP
COMMENTS ON THE USE OF 4-AP FOR CLINICAL PURPOSES AND IN STUDIES OF THE CENTRAL NERVOUS SYSTEM
Chapter 9. The Influence of 4-Aminopyridine on Parasympathetic Transmission
Part 3: Aminopyridines and the Release of Chemical Transmitters: Contrast with Apamin
Chapter 10. Structure - Activity Relationships Amongst Aminopyridines
ACTIONS ON ELECTRICALLY EXCITABLE MEMBRANES
ACTIONS ON THE CENTRAL NERVOUS SYSTEM
EPPECTS ON NEUROMUSCULAR TRANSMISSION
EFFECTS ON PARASYMPATHETIC NEUROEFFECTOR TRANSMISSION
EFFECTS ON SYMPATHETIC NEUROEFFECTOR TRANSMISSION
EFFECTS ON CARDIAC MUSCLE
PRESENT AND POTENTIAL CLINICAL USES OF AMINOPYRIDINES
Chapter 11. Aminopyridine as a Tool to Investigate the Mechanism of Acetylcholine Release at the Nerve Electroplaque Junction
Chapter 12. Intramembrane Particles Changes: A Constant Feature of the Release Mechanism
PRESYNAPTIC MEMBRANE MODIFICATIONS IN THE COURSE OF ACh RELEASE
SYNAPTOSOMAL ACh CONTENT AND COMPARTMENTATION
CONTINUOUS DETERMINATION OF ACh RELEASE
THE MECHANISM OF ACh RELEASE
Chapter 13. Effect of Aminopyridine and Related Drugs on Catecholamine Release
Chapter 14. Some Differences in the Blockade of Potassium Permeabilities by Apamin and the Aminopyridines
PERIPHERAL ACTIONS OF APAMIN
APAMIN IN RELATION TO THE AMINOPYRIDINES
Part 4: Miscellaneous Actions of Aminopyridines and Related Compounds: Poster Commimications
Chapter 15. The Action of Morphine Dependence on the Convulsive Effect of 4-Aminopyri and Other Drugs
Chapter 16. Antagonism to Dopaminergic Stereotypy, and Convulsant and Hypertensive Effects by 2-Amino-4-Methylpyridine
Chapter 17. 4-Aminopyridine (4AP) Enhances Acetylcholine Output from the Rat Cerebral Cortex in vivo
Chapter 18. 4-Aminopyridine as a Tool to Elucidate Different Actions of Botulinum A and Tetanus Toxin at the Mouse Neuromuscular Junction
Chapter 19. Antagonism of the Myoneural Activity of Antibiotics, Local Anesthetics and General Anesthetics By 4-APYR
Chapter 20. Increased Tetanic Fade Produced by 3,4-Diaminopyridine in the Presence of Neuromuscular Blocking Agents
Chapter 21. Effect of 4-Aminopyridine on the Electrical Activity of the Hippocampus and the Cerebellum
Chapter 22. Cardiac Effects of 4-Aminoquinoline on Mammalian and Amphibian Isolated Preparations An Electrophysiological Study
Chapter 23. Facilitatory Effects of Aminopyridines on Synaptic Transmission in the Sixth Abdominal Ganglion of the Cockroach
Chapter 24. The Effect of 3-,4-AP and 3,4-DAP on the Evoked Activity of the Pyramidal Cell Layer (CA 1,2) of the Hippocampus An in vitro Study
Chapter 25. Fast and Slow Automatic Activity of Squid Giant Axons Induced by 4-Aminopyridine
Chapter 26. The Ability of 4-Aminopyridine and 3,4-Diaminopyridine to Gross the Blood-Brain Barrier can Account for Their Difference in Toxicity
Chapter 27. Action of 4AP and TEA on Presynaptic Currents in Mammalian Motor Endings
Chapter 28. Protein Synthesis in Brain Subcellular Fractions Effect of 4-Amino-Pyridine
Chapter 29. Effects of 4-Hydroxypyridine on Transmitter Release at the Neuromuscular Junction
Chapter 30. 4-Aminopyridine Analogs of Novel Chemical Structure
Chapter 31. Excitatory Action of Imidazole on Evoked Transmitter Release from the Phrenic Nerve and on Potassium-stimulated 45Ca Uptake by Synaptosomes in the Rat
Chapter 32. Aminopyridine Effects on Molecular Models in Myopathic States
Chapter 33. Effects of Pyridine on the Frog Rectus Abdominis Muscle
Chapter 34. 4-Aminopyridine and Pre-synaptic Modulation of Transmitter Release in Aplysia
Chapter 35. Naloxone, 4-Aminopyridine and Physostigmine as Antagonists of Morphine in Rabbits
Chapter 36. Anti-Curare Action of 4-Aminopyridine and 4-Aminopyridine-like Substances
Chapter 37. 4-Aminopyridine Reversal of Morphine Analgesia
Chapter 38. 4-Aminopyridine as Antagonist of the Cardio vascular and Neuromuscular Depressant Effects of Kanamycin in Rats
Chapter 39. Further Actions of Aminopyridines on Muscle and Nerve: Short Communications
Chapter 40. Effects of 4-Aminopyridine on Mammalian Peripheral and Central Neurones
Chapter 41. Interactions of Aminopyridines and Related Compounds with Ionic Channels in the Isolated Cockroach Axon
Chapter 42. 4-Aminopyridine-induced Alteration in the Receptive Field of Cuneate and Gracile Neurones
Chapter 43. Effect of 4-Aminopyridine on the Desensitisation of the Rat Diaphragm Caused by Carbachol
Chapter 44. The Effects of 4-Aminopyridine on Neuromuscular Block Produced by Succinyldicholine
Chapter 45. Chemical Modulators: Their Molecular Characteristics and Kinetics of Actions
Part 5: Aminopyridines and Skeletal, Smooth and Cardiac Muscle
Chapter 46. Effects of 4-Aminopyridine on Contractile Properties of Skeletal Muscle
Chapter 47. Effects of 4-Aminopyridine on Cardiac Muscle
Chapter 48. Effects of 4-Aminopyridine on Isometric Force [Ca++] Relations in Mammalian Slow and Fast Twitch Skinned Muscle Fibres
Chapter 49. 4-Aminopyridine and Outward Membrane Currents in Rat Uterine Smooth Muscle at Various Stages of Pregnancy
Chapter 50. Effects of 4-Aminopyridine on Membrane Currents in the Pace-maker Voltage Range of Sheep Cardiac Purkinje Fibres
Chapter 51. Is the Cardiotonic Effect of Aminopyridines and Aminopyrimidines in vitro A Consequence of Increased Extracellular pH?
Part 6: Clinical Applications of Aminopyridines
Chapter 52. Therapeutic Applications of Aminopyridines in Diseases of Neuromuscular Transmission
EFFECTS IN VITRO ON INTERCOSTAL MUSCLE
EFFECTS IN VIVO IN EATON-LAMBERT SYNDROME
EFFECTS IN VIVO IN MYASTHENIA GRAVIS
Chapter 53. Use of 4-Ammopyridine in Human Botulism
RESULTS OF SINGLE AND DOUBLE DOSE ADMINISTRATION OF 4-AP
Chapter 54. Therapeutic Applications of 4-Aminopyridine in Anaesthesia
CENTRAL NERVOUS SYSTEM (CNS)
Chapter 55. Effects of 3,4-Diaminopyridine in Cynomolgus Monkeys Poisoned with Type A Botulinum Toxin
Part 7: Further Miscellaneous Actions of Aminopyridines and Related Compounds Short Communications
Chapter 56. Potassium Channel Block by S-Methylthiouronium, A Pharmacological Analogue of 4-Aminopyridine
Chapter 57. Differences in Actions of 4-Aminopyridine and 4-Methyl-2-Aminopyridine
Chapter 58. Effects of Aminopyridines in Avian Muscular Dystrophy
Chapter 59. Comparison of the Actions of Dendrotoxin, A Facihtatory Neurotoxin, and 3,4-Diaminopyridine on Neuromuscular Transmission
Chapter 60. Effects of Aminopyridines on Parasympathetic Neuro-effector Transmission in the Heart
Chapter 61. Effects of 4-Aminopyridine on Endocrine Cells
Chapter 62. An Electroencephalographic Study of 4-Aminopyridine in Conscious Volunteers