Cardiovascular Physiology: Microcirculation and Capillary Exchange :Proceedings of the 28th International Congress of Physiological Sciences, Budapest, 1980

Publication subTitle :Proceedings of the 28th International Congress of Physiological Sciences, Budapest, 1980

Author: Kovàch   A. G. B.;Hamar   J.;Szabó   L.  

Publisher: Elsevier Science‎

Publication year: 2013

E-ISBN: 9781483189956

P-ISBN(Paperback): 9780080268194

P-ISBN(Hardback):  9780080268194

Subject: R Medicine and Health

Language: ENG

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Description

Advances in Physiological Sciences, Volume 7: Cardiovascular Physiology: Microcirculation and Capillary Exchange is a collection of papers that tackles the advances in the understanding of microcirculation and capillary exchange.
The text first details the coordination of microcirculatory function with oxygen demand in skeletal muscle, and then proceeds to discussing the role of intravascular pressure in the regulation of the microcirculation. Next, the selection covers the circulatory actions of prostacyclin and thromboxane, along with the routes of transcapillary transport. The last two parts of the text deal with the lymphatic system and blood-brain barrier.
The book will be of great interest to health professionals, particularly cardiologists and cardiovascular surgeons.

Chapter

CAPILLARY BLOOD OXYGEN CONTENT

TISSUE PO2 DURING FUNCTIONAL HYPEREMIA

REFERENCES

CHAPTER 2. THE ROLE OF INTRAVASCULAR PRESSURE IN REGULATION OF THE MICROCIRCULATION

Introduction

Response to Dynamic Stretch

Myogenic Response to Sustained Force

Mechanism of the Myogenic Response

Interaction of Myogenic and Metabolic Factors

Interaction of Myogenic and Neural Factors

Integration of Arteriolar Behavior in A. Network Model

Conclusions

References

PART 1: CIRCULATORY ACTIONS OF PROSTACYCLIN AND THROMBOXANE

CHAPTER 3. ARACHIDONIC ACID METABOLITES IN THE CARDIOVASCULAR SYSTEM

Anti-thrombotic and haemostatic effects of prostacyclin

Prostacyclin - Thromboxane A2 balance and anti-thrombotic therapy

Cardiovascular effects of Prostacyclin

Effects of prostacyclin in man

Prostacyclin and Extracorporeal Circulations

Prostacyclin and Heparin

Perspectives in the development of new antithrombotic therapy

REFERENCES

CHAPTER 4. PROSTACYCLIN AND ATHEROSCLEROSIS

CLINICAL TRIALS

DISCUSSION

REFERENCE LIST

CHAPTER 5. PROSTACYCLIN RELEASED BY ANGIOTENSINS FROM LUNGS AND ISOLATED VASCULAR TISSUE

INTRODUCTION

PROSTACYCLIN RELEASED FROM LUNGS BY ANGIOTENSINS

PROSTACYCLIN RELEASED FROM OTHER VASCULAR BEDS BY ANGIOTENSINS

MECHANISM OF ANGIOTENSIN-INDUCED RELEASE OF PROSTACYCLIN

ANGIOTENS IN CONVERSION AND PR0STACYCLIN RELEASE

REFERENCES

CHAPTER 6. EFFECT OF PROSTACYCLIN ON THE SYMPATHETICALLY-MEDIATED NOCICEPTIVE CARDIOVASCULAR REFLEX

ACTIONS OF PROSTACYCLIN ON NICOTINE-INDUCED VAGALLY-MEDIATED CHEMOREFLEX

DISCUSSION AND CONCLUSIONS

ACKNOWLEDGEMENTS

REFERENCES

CHAPTER 7. ROLE OF PROSTAGLANDINS IN THE REGULATION OF BLOOD PRESSURE AND BLOOD FLOW

MICROCIRCULATORY STUDIES WITH PROSTAGLANDINS

ACKNOWLEDGEMENTS

REFERENCES

CHAPTER 8. CARDIOVASCULAR ACTIONS OF TWO THROMBOXANE A2 ANALOGS

Acknowledgements

REFERENCES

CHAPTER 9. COMPARISON OF VASODEPRESSOR AND VASODILATOR EFFECTS OF PROSTAGLANDINS E1,E2, I2 AND 6-KETO-E

INTRODUCTION

METHODS

RESULTS

DISCUSSION

REFERENCES

CHAPTER 10. CAPILLARIES AS THE SOURCE OF PROSTACYCLIN AND PROSTAGLANDIN SYNTHETASES IN BRAIN

ABSTRACT

INTRODUCTION

MATERIALS AND METHODS

RESULTS

DISCUSSION

ACKNOWLEDGEMENT

REFERENCES

CHAPTER 11. CONCLUDING REMARKS ON CIRCULATORY ACTIONS OF PROSTACYCLIN AND THROMBOXANE

PART 2: ROUTES OF TRANSCAPILLARY TRANSPORT: CORRELATION OF STRUCTURE AND FUNCTION

CHAPTER 12 INTRODUCTION TO ROUTES OF TRANSCAPILLARY TRANSPORT: CORRELATION OF STRUCTURE AND FUNCTION

CHAPTER 13. VESICLES AND/OR CONTINUOUS CHANNELS

REFERENCES

CHAPTER 14. FUNCTIONS OF ENDOTHELIAL JUNCTIONS

REFERENCES

CHAPTER 15. THE FROG MESENTERIC CAPILLARY AS A MODEL OF MAMMALIAN CONTINUOUS CAPILLARIES

Materials and methods

Results

Discussion

REFERENCES

CHAPTER 16. INCREASED PERMEABILITY OF THE ARTERIOCAPILLARY SEGMENT IN HYPERTENSION

Acute arterial hypertension

Chronic arterial hypertension

REFERENCES

CHAPTER 17. MICROCIRCULATION AND PERMEABILITY OF MICROVESSELS UNDER THE CONDITION OF PHYSICAL LOAD

REFERENCES

CHAPTER 18. TRANSCAPILLARY FLUID FLUX INDUCED BY TRANSIENT HYPERTONIC DISTURBANCES

METHOD

THEORETICAL ANALYSIS

RESULTS

DISCUSSION

REFERENCES

AKNOWLEDGEMENT

CHAPTER 19. THE EFFECT OF ALBUMIN ON THE SIZE-LIMITING STRUCTURES DETERMINING TRANSCAPILLARY EXCHANGE

INTRODUCTION

METHODS

RESULTS

DISCUSSION

CONCLUSION

REFERENCES

CHAPTER 20. CONCLUDING REMARKS ON TRANSCAPILLARY TRANSPORT: CORRELATION OF STRUCTURE AND FUNCTION

PART 3: THE LYMPHATIC SYSTEM: FUNCTIONING AND INTERRELATIONSHIPS

CHAPTER 21. INTRALYMPHATIC VS. TISSUE PRESSURE IN THE EDEMATOUS BAT WING

METHODS

RESULTS

DISCUSSION

REFERENCES

CHAPTER 22. CONCENTRATION OF MACROMOLECULES IN THE TISSUE AND LYMPHATICS

Acknowledgments.

References.

CHAPTER 23. RELATIONS BETWEEN TISSUE FLUID AND LYMPH IN THE LUNGS: THE MACROSCOPIC ORGANIZATION OF THE INTERSTITIUM

References

CHAPTER 24. THE INITIAL LYMPHATIC CYCLE AND THE FORCES RESPONSIBLE FOR IT

THE MORPHOLOGY OF THE INITIAL LYMPHATIC CYCLE

POSSIBLE FORCES CAUSING THE ENTRY OF FLUID, ETC., INTO LYMPHATICS

EVIDENCE CONCERNING THE COLLOIDAL OSMOTIC PRESSURE HYPOTHESIS

CONCLUSION

REFERENCES

CHAPTER 25. ARE PRESSURES IN IMPLANTED CAPSULES A VALID MEASURE OF INTERSTITIAL FLUID PRESSURES?

RE-EQUILIBRATION OF CAPSULE PRESSURE MEASUREMENTS AFTER PERTUBATIONS

MEASUREMENT OF CHANGES IN CAPSULE PRESSURE AND SIMULTANEOUS CHANGES IN NEEDLE PRESSURE IN VERY EDEMATOUS TISSUE

SHAPE OF THE INTERSTITIAL FLUID VOLUME-PRESSURE CURVE AS MEASURED USING THE CAPSULE METHOD

MEASUREMENT OF CAPSULE PRESSURES WHEN THE PLASMA COLLOID OSMOTIC PRESSURE IS GREATLY INCREASED

COMMENT

REFERENCES

CHAPTER 26. DETERMINANTS OF LYMPH FLOW AND COMPOSITION

EXPERIMENTAL

RESULTS

REFERENCES

CHAPTER 27. MACROMOLECULAR REMOVAL VIA BLOOD AND LYMPH

REFERENCES

CHAPTER 28. INTERSTITIAL-TO-BLOOD MOVEMENT OF PLASMA PROTEINS

INTRODUCTION

METHODS

RESULTS

DISCUSSION

REFERENCES

CHAPTER 29. CONCLUDING REMARKS ON THE LYMPHATIC SYSTEM: FUNCTIONING AND INTERRELATIONSHIPS

PART 4: BLOOD-BRAIN BARRIER

CHAPTER 30. THE BLOOD-BRAIN BARRIER REVISITED

THE BLOOD-BRAIN BARRIER AS AN EPITHELIUM

REFERENCES

CHAPTER 31. STRUCTURAL ELEMENTS COMPRISING THE BLOOD-BRAIN BARRIER

1. Fine structural features of the capillary endothelium

2. Fine structural changes of the capillary endothelium in pathological circumstances

3. Enzymes confined to the capillary endothelium

4. Practical considerations

REFERENCES

CHAPTER 32. INSULIN AND THE BLOOD-BRAIN BARRIER

REFERENCES

CHAPTER 33. PROPERTIES OF TRANSPORT PROCESSES OF THE BLOOD-BRAIN BARRIER DURING DEVELOPMENT

REFERENCES

CHAPTER 34. REGULATION AND ADAPTATION OF SUBSTRATE TRANSPORT TO BRAIN

Substrates

Methods

Acute change of metabolic rate

Acute change of plasma concentration

Chronic change of plasma concentration

Conclusions

REFERENCES

CHAPTER 35. IN VITRO INVESTIGATIONS OF THE BLOODBRAIN BARRIER: ISOLATION AND CULTURE OF BRAIN CAPILLARY ENDOTHELIAL CELLS

REFERENCES

CHAPTER 36. EFFECT OF HISTAMINE ON THE PERMEABILITY, FINE STRUCTURE AND ADENYLATE CYCLASE ACTIVITY OF BRAIN CAPILLARIES

References

CHAPTER 37. HOMEOSTASIS OF THE COMPOSITION OF CEREBRAL INTERSTITIAL FLUID

CONCLUSIONS

REFERENCES

CHAPTER 38. CONVECTION OF BRAIN INTERSTITIAL FLUID

Intracerebral channels of flow

Removal of radiolabelled extracellular tracers from brain

Estimation of the rate of ISF production

The mechanism of ISF production

REFERENCES

CHAPTER 39. PATHOLOGICAL OPENING OF THE BBB

REFERENCES

CHAPTER 40. SPECULATIONS ON FUNCTIONS OF THE BLOOD-BRAIN BARRIER

INTRODUCTION

SPECIFIC POSSIBLE FUNCTIONS

INDEX

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