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Synthesis, Biochemical Evaluation and Rationalisation of a Series of (3-O-Sulfonate) Derivatives of Estrone (E1) as Probes of the Active Site of Type 3 of the 17&bgr;-Hydroxysteroid Dehydrogenase (17&bgr;-HSD) Family of Enzymes

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Synthesis, Biochemical Evaluation and Rationalisation of a Series of 3,5- Dibromo Derivatives of 4-Hydroxyphenyl Ketone-Based Compounds as Probes of the Active Site of Type 3 of 17&bgr;-Hydroxysteroid Dehydrogenase (17&bgr;-HSD3) and the Role of Hydrogen Bonding Interaction in the Inhibition of 17&bgr;-HSD3

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The Derivation of a Potential Transition-State for the Reduction Reaction Catalysed by 17&bgr; -Hydroxysteroid Dehydrogenase Type 3 (17&bgr; -HSD) - An Approximate Representation of its Active Site for Use in Drug Design and Discovery

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Synthesis and Biochemical Evaluation of a Series of Methanesulfonate Derivatives of 4-Hydroxyphenyl Ketone as Probes of the Active Site of Type 3 OF 17#946;-Hydroxysteroid Dehydrogenase Family of Enzymes

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