Pyrazolines: A Biological Review

Publisher: Bentham Science Publishers

E-ISSN: 1875-5607|13|6|921-931

ISSN: 1389-5575

Source: Mini Reviews in Medicinal Chemistry, Vol.13, Iss.6, 2013-05, pp. : 921-931

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Abstract

Pyrazoline is an important five membered nitrogen heterocycle, which has been extensively researched upon. The ring is quite stable and has inspired chemists to carry out various structural variations in the ring. This has propelled the development of distinct pyrazolines with an array of pharmacological activities viz. anti-inflammatory, analgesic, antimicrobial, anticancer, antidepressant etc. The review aims at highlighting this pharmacological diversity of pyrazolines. The review is a gist of latest work done describing the pharmacological aspects and potential of pyrazoline ring.