Publisher： Bentham Science Publishers
E-ISSN： 1875-533x|22|7|866-877
ISSN： 0929-8673
Source： Current Medicinal Chemistry, Vol.22, Iss.7, 2015-03, pp. : 866-877
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
Until recently, P2X receptors have not received much attention in the context of immunology and inflammation. While this is justified to a certain extent for P2X1, P2X2, P2X3, P2X5 and P2X6, which still await identification of a convincing role in the pathophysiology of immune cells, it is clearly not any more the case for P2X4 and even more so for P2X7, a molecule that has achieved the status of an essential, nonredundant, immunomodulatory receptor. In this review I will highlight the most important inflammatory responses participated by P2X receptors.
Related content
Current Medicinal Chemistry, Vol. 22, Iss. 7, 2015-03 ,pp. :
Access to resources
Recommend
Purine Ionotropic (P2X) Receptors
Current Pharmaceutical Design, Vol. 13, Iss. 23, 2007-08 ,pp. :
The Role of P2X Receptors in Bone Biology
Current Medicinal Chemistry, Vol. 22, Iss. 7, 2015-01 ,pp. :
P2X Receptors, Sensory Neurons and Pain
Current Medicinal Chemistry, Vol. 22, Iss. 7, 2015-03 ,pp. :
Emerging Roles of P2X Receptors in Cancer
Current Medicinal Chemistry, Vol. 22, Iss. 7, 2015-03 ,pp. :