Publisher： Bentham Science Publishers
E-ISSN： 1875-6638|7|5|334-344
ISSN： 1573-4064
Source： Medicinal Chemistry, Vol.7, Iss.5, 2011-09, pp. : 334-344
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Abstract
The labeling of probes with fluorine-18 [18F, &bgr;(+); 96.7%] continues to play a considerably important role in the development of positron emission tomography (PET) as a modality for both clinical research and clinical diagnoses. This review summarizes the strategies and recent developments in the fluorine-18 labeling of probes for PET imaging. Problems and issues relating to the practical production of fluorine-18 currently in widespread use are also discussed.
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