

Publisher: Bentham Science Publishers
E-ISSN: 1874-4745|3|4|197-204
ISSN: 1874-4737
Source: Current Drug Abuse Reviews, Vol.3, Iss.4, 2010-12, pp. : 197-204
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
Alcoholism's heritability has been convincingly documented but the question of why a disorder that is so damaging to the individual and to society should continue to persist is still baffling. A widely held assumption is that whatever genotype is involved, its components must originally have conferred survival value else it would never have evolved. The corollary to that assumption is that when conditions favoring that genotype changed, the former advantages became detrimental. However, the genotype has persisted because it does not affect sexual function, if at all, until after peak reproductive years. An appreciation of the evolutionary biology and the historical-cultural context associated with alcohol consumption may lead not only to a better understanding of this disorder but to treatment alternatives based on that understanding.
Related content


Evolutionary Origins of Animal Skeletal Biomineralization
Cells Tissues Organs, Vol. 194, Iss. 2-4, 2011-05 ,pp. :


Comorbidity between depression and alcoholism
By Trenckmann U. Voigt W. Piayda H.
European Neuropsychopharmacology, Vol. 5, Iss. 3, 1995-09 ,pp. :


Emerging drugs to treat alcoholism
By Soyka Michael Rösner Susanne
Expert Opinion on Emerging Drugs, Vol. 15, Iss. 4, 2010-12 ,pp. :




Is there a role for neurosteroids in alcoholism?
By Romeo E. Pompili E. di Michele F. Furnari C. Fucci P. Pasini A.
European Neuropsychopharmacology, Vol. 5, Iss. 3, 1995-09 ,pp. :