Design of Magnetic Nanoparticles-Assisted Drug Delivery System

Publisher: Bentham Science Publishers

E-ISSN: 1873-4286|17|22|2331-2351

ISSN: 1381-6128

Source: Current Pharmaceutical Design, Vol.17, Iss.22, 2011-07, pp. : 2331-2351

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Abstract

Magnetic nanoparticles (MNPs) have been designed for multifaceted applications such as contrast agents in magnetic resonance imaging (MRI) diagnosis, drug/gene carriers for different kinds of therapeutic agents, tissue repair, hyperthermia, immunoassay, and cell separation/sensing. This review highlights synthesis methods, stabilizers used for surface coating on MNPs, and target ligands for ferrying payloads to an interested disease area. Some of the recent biomedical applications of MNPs in the field of drug and DNA targeting delivery are extensively reviewed.