Publisher: John Wiley & Sons Inc
E-ISSN: 1521-4095|27|22|3437-3443
ISSN: 0935-9648
Source: ADVANCED MATERIALS, Vol.27, Iss.22, 2015-06, pp. : 3437-3443
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
A hybrid nanomaterial integrating unique toxin‐absorbing nanosponges with hydrogel is developed for local antivirulence therapy against methicillin‐resistant Staphylococcus aureus (MRSA) infection. The hydrogel composition is optimized to retain toxin nanosponges after administration while not compromising toxin transport into the gel for neutralization. Mice treated with the nanosponge–hydrogel hybrid show markedly reduced MRSA skin lesion development.
Related content
JOURNAL OF PHARMACY AND PHARMACOLOGY: AN INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCE, Vol. 67, Iss. 10, 2015-10 ,pp. :