Organic Chemistry Concepts and Applications for Medicinal Chemistry

Author: Rice   Joseph E.  

Publisher: Elsevier Science‎

Publication year: 2014

E-ISBN: 9780128008324

P-ISBN(Paperback): 9780128007396

P-ISBN(Hardback):  9780128007396

Subject: O62 Organic Chemistry

Language: ENG

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Description

Organic Chemistry Concepts and Applications for Medicinal Chemistry provides a valuable refresher for understanding the relationship between chemical bonding and those molecular properties that help to determine medicinal activity. This book explores the basic aspects of structural organic chemistry without going into the various classes of reactions. Two medicinal chemistry concepts are also introduced: partition coefficients and the nomenclature of cyclic and polycyclic ring systems that comprise a large number of drug molecules. Given the systematic name of a drug, the reader is guided through the process of drawing an accurate chemical structure. By emphasizing the relationship between structure and properties, this book gives readers the connections to more fully comprehend, retain, apply, and build upon their organic chemistry background in further chemistry study, practice, and exams.

  • Focused approach to review those organic chemistry concepts that are most important for medicinal chemistry practice and understanding
  • Accessible content to refresh the reader's knowledge of bonding, structure, functional groups, stereochemistry, and more
  • Appropriate level of coverage for students in organic chemistry, medicinal chemistry, and related areas; individuals seeking content review for graduate and medical courses and exams; pharmaceutical patent attorneys; and chemists and scientists requiring a review of pertinent material

Chapter

Front Cover

pp.:  1 – 4

Copyright

pp.:  5 – 6

DEDICATION

pp.:  6 – 8

CONTENTS

pp.:  8 – 10

PREFACE

pp.:  10 – 12

Chapter 1 - Bonding in Organic Compounds

pp.:  12 – 38

Chapter 2 - The Three-Dimensional Structure of Organic Compounds

pp.:  38 – 62

Chapter 3 - Functional Groups

pp.:  62 – 78

CHAPTER 4 - ACIDS AND BASES*

pp.:  78 – 96

Chapter 5 - Partition Coefficients

pp.:  96 – 104

Chapter 6 - The Nomenclature of Cyclic and Polycyclic Compounds

pp.:  104 – 156

Chapter 7 - Drug Metabolism

pp.:  156 – 214

INDEX

pp.:  214 – 220

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