Aspergillus fumigatus and Aspergillosis

Author: Latgé  

Publisher: American Society for Microbiology‎

Publication year: 2009

E-ISBN: 9781555815523

P-ISBN(Hardback):  9781555814380

Subject: Q1 General Biology

Language: ENG

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Chapter

I: THE SPECIES

2 Morphology and Reproductive Mode of Aspergillus fumigatus

3 Molecular Methods for Species Identification and Strain Typing of Aspergillus fumigatus

4 Aspergillus fumigatus Specificities as Deduced from Comparative Genomics

5 Essential Genes in Aspergillus fumigatus

II: GROWTH AND SENSING, OR RESISTING ENVIRONMENTAL STRESS

6 Aspects of Primary Carbon and Nitrogen Metabolism

7 Phospholipases of Aspergillus fumigatus

8 Aspergillus fumigatus Secreted Proteases

9 Cations (Zn, Fe)

10 Conidial Germination in Aspergillus fumigatus

11 Growth Polarity

12 Biofilm Formation in Aspergillus fumigatus

13 Signal Transduction

14 Cell Wall of Aspergillus fumigatus: a Dynamic Structure

15 Genetic Regulation of Aspergillus Secondary Metabolites and Their Role in Fungal Pathogenesis

16 Aspergillus fumigatus: Survival and Death under Stress

III: IMMUNE DEFENSE AGAINST ASPERGILLUS

17 Reactive Oxygen Intermediates, pH, and Calcium

18 Innate Defense against Aspergillus: the Phagocyte

19 Interactions of Aspergillus with the Mucosa

20 Dendritic Cells in Aspergillus Infection and Allergy

21 CD4[sup(+)] T-Cell Responses to Aspergillus fumigatus

22 Innate Recognition of Aspergillus fumigatus by the Mammalian Immune System

IV: THE SPECTRUM OF DISEASE

23 Invasive Pulmonary Aspergillosis

24 Aspergillus Sinusitis and Cerebral Aspergillosis

25 Chronic Aspergillosis

26 Allergic Bronchopulmonary Aspergillosis

V: DIAGNOSIS

27 Histology and Radiology

28 Galactomannan and Anti-Aspergillus Antibody Detection for the Diagnosis of Invasive Aspergillosis

29 Aspergillus PCR

VI: THERAPY

30 Polyenes in the Treatment of Aspergillosis

31 Azoles in the Treatment of Aspergillosis

32 Echinocandins in the Treatment of Aspergillosis

33 Antifungal Drug Interactions

34 Antifungal Mechanisms of Action and Resistance

35 Immunotherapy

VII: TIMING OF ANTIFUNGAL THERAPY

36 Prophylaxis against Invasive Aspergillosis

37 Therapy of Invasive Aspergillosis: Current Consensus and Controversies

VIII: SPECIFIC PATIENT POPULATIONS

38 Invasive Aspergillosis in Solid Organ Transplant Recipients

39 Invasive Aspergillosis in Malignancy and Stem Cell Transplant Recipients

40 Invasive Aspergillosis in Pediatric Patients

IX: FUTURE DIRECTIONS

41 A Perspective View of Aspergillus fumigatus Research for the Next Ten Years

Index

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