Chapter
Chapter 1. K+ Channels: a Survey and a Case Study of Kch of Escherichia coli
THE INVISIBLE BIOLOGICAL WORLD
A MENAGERIE OF K+ CHANNELS
Kch, THE K+ CHANNEL OF E. COLI
Chapter 2. The Ktn Domain and Its Role as a Channel and Transporter Regulator
STRUCTURE OF THE Ktn DOMAIN
ROLE OF Ktn DOMAINS IN REGULATION OF TRANSPORT
Chapter 3. Deciphering Streptomyces lividans KcsA as a K Channel Model
GENERAL FEATURES OF STREPTOMYCETES
CHANNEL ACTIVITY WITHIN GIANT PROTOPLAST VESICLES
HIGH SYNTHESIS LEVELS AND PURIFICATION OF KcsA
FUNCTIONAL RECONSTITUTION IN A BILAYER
GENERAL FEATURES OF THE RECONSTITUTED FUNCTIONAL KcsA CHANNEL
CHANNEL OPENING AND CATION SELECTIVITY AT LOW pH
EFFECTS OF ELECTROCHEMICAL GRADIENT, pH, AND TEMPERATURE ON OPENING AND SELECTIVITY
AMINO ACIDS AFFECTING ASSEMBLY AND ACTIVITY
DYNAMIC CHANGES WITHIN THE PERMEATION PATHWAY
INTERACTION OF KcsA WITH PHOSPHOLIPIDS
ASSEMBLY OF KcsA WITHIN THE INNER MEMBRANE OF AN E. COLI HOST
INTERACTION OF KcsA WITH NONPROTEIN MOLECULES FROM AN E. COLI HOST
MODULE SHUFFLING AMONG KcsA AND EUKARYOTIC CHANNEL PROTEINS
CLOSE AND DISTANT RELATIVES OF KcsA
THE CRYSTAL STRUCTURE OF KcsA: AN OPEN OR CLOSED CHANNEL?
VIRAL Kcv CHANNELS ARE SMALLER THAN KcsA
Chapter 4. The Molecular Basis of K+ Channel Gating
CORE CHANNEL DOMAIN STRUCTURE
K+ CHANNEL OPEN STRUCTURES
RCK DOMAIN-CONTAINING CHANNELS
CONFORMATIONAL MOVEMENT OF RCK DOMAINS AND GATING
Chapter 5. Glutamate-Activated Channels
ANIMAL GLUTAMATE RECEPTORS
PROKARYOTIC GLUTAMATE RECEPTORS
PLANT GLUTAMATE RECEPTORS
EVOLUTIONARY RELATIONSHIP
Chapter 6. Voltage-Gated K+ Channels
CREVASSE MODELS OF ACTIVATION GATING
MODELS BASED ON THE CRYSTAL STRUCTURE OF THE ISOLATED VOLTAGE-SENSING DOMAIN OF KvAP
OTHER TYPES OF PROKARYOTIC Kv CHANNELS
Chapter 7. Inward Rectifier K+ Channels
Chapter 8. From Prokaryotes to Eukaryotes: Molecular Modeling and Simulation Studies of Ion Channels
Chapter 9. Towards an Understanding of Membrane Channels
PERMEATION AND SELECTIVITY IN AQUAPORIN WATER CHANNELS
ION AND WATER PERMEATION IN ALPHA-HEMOLYSIN
PERMEATION AND GATING OF MECHANOSENSITIVE CHANNELS
Chapter 10. Bacterial Na Channels: Progenitors, Progeny, or Parallel Evolution?
A FAMILY OF VOLTAGE-GATED BACTERIAL SODIUM CHANNELS
NaChBac OR CaChBac? FROM SEQUENCE TO FUNCTION
PROSPECTS FOR THE FUTURE: A NEW BIOPHYSICAL MODEL
Chapter 11. The CLC Family of Proteins: Chloride Transporters and Channels
SOME GENERAL CHARACTERISTICS OF THIS FAMILY
EVOLUTIONARY RELATIONSHIPS
THE MUSCLE-TYPE CLC CHANNELS (ClC-0 AND ClC-1)
PEPTIDE MOTIFS IN ClC-Hs1
NONVERTEBRATE CLC PROTEINS
ROLE OF CLC CHLORIDE CHANNELS IN DISEASE
Chapter 12. The Bacterial Mechanosensitive Channel MscS and Its Extended Family
CHARACTERIZING MscS ACTIVITY
REVEALING STRUCTURAL FEATURES OF THE MscS PROTEIN
MODELS FOR GATING AND MODULATING MscS ACTIVITY
THE MscS EXTENDED FAMILY: SPECULATION OF FUNCTION AND FORM
Chapter 13. MscL, a Bacterial Mechanosensitive Channel
BACTERIAL MECHANOSENSITIVE CHANNELS AS MODEL SYSTEMS
PREPARATIONS FOR BACTERIAL CHANNEL RECORDING
MscL ACTIVITIES IN NATIVE MEMBRANES AND LIPOSOMES
EXPERIMENTS VERSUS MODELS
CURRENT TRENDS AND PERSPECTIVES
Chapter 14. The Role of Bacterial Channels in Cell Physiology
POTENTIAL ROLES OF BACTERIAL ION CHANNELS
ESTABLISHED FUNCTIONS OF ION CHANNELS IN BACTERIAL PHYSIOLOGY
GLUTATHIONE-GATED K+ EFFLUX SYSTEMS
SOLUTE-SPECIFIC (GATED) PORES