Chapter
SECTION I: THE ORGANISMS, THEIR GENOMICS, AND VARIABILITY
2 An Introduction to the Medically Important Candida Species
3 Comparative Genomics of Candida Species
4 The Genetic Code of the Candida CTG Clade
5 Genome Instability and DNA Repair
7 Detection and Clinical Significance of Variability among Candida Isolates
8 Cell Cycle and Growth Control in Candida Species
SECTION II: HOST-PATHOGEN INTERACTIONS (THE HOST)
9 Immunology of Invasive Candidiasis
10 Mucosal Immunity to Candida albicans
11 Innate Immunity to Candida Infections
12 Vaccines and Passive Immunity against Candidiasis
13 Salivary Histatins: Structure, Function, and Mechanisms of Antifungal Activity
SECTION III: HOST-PATHOGEN INTERACTIONS THE PATHOGEN)
14 The Cell Wall: Glycoproteins, Remodeling, and Regulation
15 Stress Responses in Candida
16 Adhesins in Opportunistic Fungal Pathogens
17 Encounters with Mammalian Cells: Survival Strategies of Candida Species
18 Gene Expression during the Distinct Stages of Candidiasis
19 Biofilm Formation in Candida albicans
20 Candida spp. in Microbial Populations and Communities: Molecular Interactions and Biological Importance
21 Back to the Future: Candida Mitochondria and Energetics
SECTION IV: ANTIFUNGAL DRUGS, DRUG RESISTANCE, AND DISCOVERY
22 Antifungals: Drug Class, Mechanisms of Action, Pharmacokinetics/Pharmacodynamics, Drug-Drug Interactions, Toxicity, and Clinical Use
23 The Impact of Antifungal Drug Resistance in the Clinic
24 Insights in Antifungal Drug Discovery
25 Multidrug Resistance Transcriptional Regulatory Networks in Candida
SECTION V: CANDIDIASIS, EVOLVING DIAGNOSTICS, AND TREATMENT PARADIGMS
27 Systemic Candidiasis: Candidemia and Deep-Organ Infections
28 New Developments in Diagnostics and Management of Invasive Candidiasis
29 The Epidemiology of Invasive Candidiasis
SECTION VI: COOL TOOLS FOR RESEARCH
30 Cool Tools 1: Development and Application of a Candida albicans Two-Hybrid System
31 Cool Tools 2: Development of a Candida albicans Cell Surface Protein Microarray
32 Cool Tools 3: Large-Scale Genetic Interaction Screening in Candida albicans
33 Cool Tools 4: Imaging Candida Infections in the Live Host
34 Cool Tools 5: The Candida albicans ORFeome Project
Candida and Candidiasis, Second Edition
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