Integrative Mechanobiology ：Micro- and Nano- Techniques in Cell Mechanobiology

Publication subTitle ：Micro- and Nano- Techniques in Cell Mechanobiology

Author： Yu Sun; Deok-Ho Kim; Craig A. Simmons  

Publisher： Cambridge University Press‎

Publication year： 2015

E-ISBN: 9781316464106

P-ISBN(Paperback): 9781107078390

Subject： Q27 cellular biophysics

Keyword： 基础医学

Language： ENG

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Integrative Mechanobiology

Description

The first of its kind, this comprehensive resource integrates cellular mechanobiology with micro-nano techniques to provide unrivalled in-depth coverage of the field, including state-of-the-art methods, recent advances, and biological discoveries. Structured in two parts, the first part offers detailed analysis of innovative micro-nano techniques including FRET imaging, electron cryo-microscopy, micropost arrays, nanotopography devices, laser ablation, and computational image analysis. The second part of the book provides valuable insights into the most recent technological advances and discoveries in areas such as stem cell, heart, bone, brain, tumor, and fibroblast mechanobiology. Written by a team of leading experts and well-recognised researchers, this is an essential resource for students and researchers in biomedical engineering.

Chapter

Cover

Half-title page

Title page

Copyright page

Contents

Contributors

Preface

Part I Micro-nano techniques in cell mechanobiology

1 Nanotechnologies and FRET imaging in live cells

2 Electron microscopy and three-dimensional single-particle analysis as tools for understanding the structural basis of mechanobiology

3 Stretchable micropost array cytometry: A powerful tool for cell mechanics and mechanobiology research

4 Microscale generation of dynamic forces in cell culture systems

5 Multiscale topographical approaches for cell mechanobiology studies

6 Hydrogels with dynamically tunable properties

7 Microengineered tools for studying cell migration in electric fields

8 Laser ablation to investigate cell and tissue mechanics in vivo

9 Computational image analysis techniques for cell mechanobiology

10 Micro- and nanotools to probe cancer cell mechanics and mechanobiology

11 Stimuli-responsive polymeric substrates for cell-matrix mechanobiology

Part II Recent progress in cell mechanobiology

12 Forces of nature: Understanding the role of mechanotransduction in stem cell differentiation

13 Mechanobiological stimulation of tissue engineered blood vessels

14 Bone cell mechanobiology using micro- and nano-techniques

15 Molecular mechanisms of cellular mechanotransduction in wound healing

16 Micropost arrays as a means to assess cardiac muscle cells

17 Micro- nanofabrication for the study of biochemical and biomechanical regulation of T cell activation

18 Study of tumor angiogenesis using microfluidic approaches

19 Neuromechanobiology of the brain: Mechanics of neuronal structure, function, and pathophysiology

Index

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