Chapter
The Structure of the mGluR
The Physiological Significance of Glutamate
Specific Agonists of mGluRs
Specific Antagonists of mGluRs
The Role of Glutamate in Aggression
The Role of mGluRs in Acute Pain
The Expression Profile of mGluR Subtypes in Pain Pathways
Mechanisms of Modulation of Acute Pain by mGluRs
The Role of mGluRs in Acute Visceral Pain/Intestinal Stress
Excitotoxic and Neurotoxic Effects of Stimulating Amino Acids
The Interaction of Glutamate and Oxytocin
Neurotoxicity of Glutamate
The Role of Glutamate in Affective Diseases
The Differential Modulation of Pain by Metabotropic Glutamate Receptor Subtypes 7 and 8
Pharmacology of Group III mGlu Receptors
mGlu7 Receptor Expression
mGlu7 Receptor Knock-Out Mice
mGlu7 Receptor Role on Pain and Affective/Cognitive Disorders
mGlu8 Receptor Expression
mGlu8 Receptor Knockout Phenotype
mGlu8 Receptor Role on Pain and Affective/Cognitive Disorders
Metabotropic Glutamate Receptors and Signal Transduction System in Epileptogenesis
mGluRs and Related Signal Transduction Proteins
mGluRs in Epileptogenesis
mGluR Signal Transduction System in Epileptogenesis
Agonists and Antagonists of mGluRS in the Control of Epilepsy and Epileptogenesis
mGluR Relative Signal Proteins as Therapeutic Targets in the Control of Epilepsy and Epileptogenesis
Metabotropic Glutamate Receptors: Classification, Structure and Roles in Disease
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