Hepatic angiosarcoma mimicking congenital cytomegalovirus infection in an infant with thrombocytopenia

Publisher: John Wiley & Sons Inc

E-ISSN: 1442-200x|57|2|e81-e83

ISSN: 1328-8067

Source: PEDIATRICS INTERNATIONAL, Vol.57, Iss.2, 2015-04, pp. : e81-e83

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

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Abstract

AbstractHepatic angiosarcomas are uncommon, highly aggressive tumors, rarely seen in children. A 3‐month‐old female infant was admitted to hospital for evaluation of multiple petechiae on her body. She had hepatosplenomegaly and scattered petechiae over her entire body. Laboratory tests indicated thrombocytopenia and positive cytomegalovirus (CMV) polymerase chain reaction. Ganciclovir was started, and the platelet count increased. After 4 months the patient was readmitted to hospital for drowsy mental status and eventually died from severe bleeding. Needle biopsy of the liver was performed after receiving written consent from the parents. Pathological findings of the liver lesion included features consistent with hepatic angiosarcoma. There have been no previous reports of hepatic angiosarcoma in Korean infants. Here, we report an infant with hepatosplenomegaly and thrombocytopenia who was diagnosed with hepatic angiosarcoma mimicking congenital CMV infection.