Description
Both acute and chronic cough are responsible for a significant number of ambulatory medical visits annually. The recent comprehensive understanding that "e;cough is a reflection of underlying disease pays tribute to the multifactorial causes, as well recognition of the respiratory and upper digestive tract as a "e;physiologic unit. This publication highlights the advances made in managing cough and brings these to otolaryngology practitioners in a concise forum, as well as presenting issues of special interest to laryngologists such as paradoxical vocal fold motion, disordered breathing, irritable larynx, evolution of the vagus as a protective circuit, the importance of cough in deglutition, and surgical interventions. Some of the topics include: The cough reflex, sensory receptors, and neurogenic mediators; Mucus and mucins; Cough and Swallowing dysfunction; Cough due to asthma, cough-variant asthma, and nonasthmatic eosinophilic bronchitis; Occupational, environmental, and irritant induced cough; Pharmacologic management; Unexplained cough; Cough in the pediatric population; and Rhinogenic laryngitis, cough and the unified airway; among others.
Chapter
DIFFERENTIAL DIAGNOSIS FOR SUBACUTE COUGH
DIFFERENTIAL DIAGNOSIS FOR CHRONIC COUGH
ANGIOTENSIN-CONVERTING ENZYME INHIBITORS
Chapter 2. Afferent Nerves Regulating the Cough Reflex: Mechanisms and Mediators of Cough in Disease
CHEMICAL AND MECHANICAL STIMULI THAT INITIATE COUGHING
AFFERENT NERVES REGULATING THE COUGH REFLEX
RAPIDLY ADAPTING RECEPTORS
AFFERENT NERVE INTERACTIONS IN COUGH AND MECHANISMS OF COUGH IN DISEASE
Chapter 3. Mucus and Mucins
COMPOSITION OF MUCUS AND PHLEGM
MUCIN SECRETION AND MUCUS CLEARANCE
UPPER AND LOWER AIRWAY MUCUS
THERAPY FOR MUCUS CLEARANCE DISORDERS
Chapter 4. Cough and Swallowing Dysfunction
FUNDAMENTALS OF SWALLOW ASSESSMENT
FUNDAMENTALS OF SWALLOWING THERAPY
Chapter 5. Vocal Cord Dysfunction, Paradoxic Vocal Fold Motion, or Laryngomalacia? Our Understanding Requires an Interdisciplinary Approach
FOCUSING ON THE BIG PICTURE
WHAT DIAGNOSES ARE IN THE DIFFERENTIAL?
DIFFERENCES AMONG PERIODIC OCCURRENCE OF LARYNGEAL OBSTRUCTION DISORDERS
PARADOXIC VOCAL FOLD MOTION
INTERMITTENT ARYTENOID REGION PROLAPSE
THE THREE CATEGORIES OF PERIODIC OCCURRENCE OF LARYNGEAL OBSTRUCTION
VOCAL CORD DYSFUNCTION AND MASS PSYCHOGENIC ILLNESS
HYPOTHESES FOR ORIGIN OF SOME LARYNGEAL DISORDERS
VOCAL CORD DYSFUNCTION MANAGEMENT
Chapter 6. Evidence for Sensory Neuropathy and Pharmacologic Management
PHARMACEUTICALS FOR TREATMENT OF PVVN
Chapter 7. The Role of Voice Therapy in the Management of Paradoxical Vocal Fold Motion, Chronic Cough, and Laryngospasm
PARADOXICAL VOCAL FOLD MOTION
APPENDIX 1. PRODUCT REFERENCES FOR RESISTANCE BREATHING DEVICES
Chapter 8. Occupational, Environmental, and Irritant-Induced Cough
RESPIRATORY TRACT EFFECTS OF IRRITANTS
OCCUPATIONAL, ENVIRONMENTAL, AND IRRITANT-INDUCED COUGH
EVOLUTION OF IRRITANT-INDUCED COUGH
IRRITANT-INDUCED COUGH, A TRPPATHY
Chapter 9. Reflux and Cough
PATHOPHYSIOLOGY OF REFLUX
THE LES AND TRANSIENT LES RELAXATION
HOW DOES REFLUX AFFECT THE LARYNX AND UPPER AIRWAY?
COUGH IN REFLUX: CLINICAL EVALUATION
COMPLICATIONS RELATED TO PPI THERAPY
Chapter 10. Rhinogenic Laryngitis, Cough, and the Unified Airway
LARYNGEAL INVOLVEMENT IN THE UNIFIED AIRWAY
MUCUS, NEUROLOGIC REFLEXES, AND NEUROGENIC INFLAMMATION
DIAGNOSIS OF CHRONIC RHINOGENIC LARYNGITIS
MODEL FOR CHRONIC RHINOGENIC LARYNGITIS
Chapter 11. Cough Due to Asthma, Cough- Variant Asthma and Non-Asthmatic Eosinophilic Bronchitis
DEFINITION, DIAGNOSIS, AND PREVALENCE
EXHALED NITRIC OXIDE AS A SURROGATE FOR SPUTUM EOSINOPHILIA
Chapter 12. The Spectrum of Nonasthmatic Inflammatory Airway Diseases in Adults
Chapter 13. Pharmacologic Management of Cough
Chapter 14. Assessing Efficacy of Therapy for Cough
SUBJECTIVE ASSESSMENTS OF COUGH
COUGH REFLEX SENSITIVITY TESTING
HEALTH-RELATED QUALITY OF LIFE
SELECTING PATIENT GROUPS FOR TESTING COUGH THERAPIES
Chapter 15. Unexplained Cough in the Adult
UNEXPLAINED VERSUS IDIOPATHIC COUGH
HOW OFTEN IS CHRONIC COUGH UNEXPLAINED, AND WHAT ARE THE POTENTIAL EXPLANATIONS?
HOW SHOULD CLINICIANS AND RESEARCHERS APPROACH THE PROBLEM?
WHAT ARE THE PITFALLS IN MANAGEMENT, AND HAVE THEY BEEN AVOIDED?
HOW OFTEN WILL CHRONIC COUGH REMAIN TRULY UNEXPLAINED AFTER THE RECOMMENDED MANAGEMENT PROTOCOL HAS BEEN FOLLOWED?
WHAT ARE THE POTENTIAL PATHOGENIC MECHANISMS TO EXPLAIN THE TRULY REFRACTORY, UNEXPLAINED COUGH?
WHAT MANAGEMENT OPTIONS ARE AVAILABLE FOR THE TRULY REFRACTORY UNEXPLAINED COUGH?
Chapter 16. Cough in the Pediatric Population
EVALUATION OF CHILDREN WITH CHRONIC COUGH
Chapter 17. Future Directions in Treating Cough
ACUTE AND CHRONIC COUGH—THE EXTENT OF THE PROBLEM
OPTIMIZING THE EXISTING PROTOCOLS FOR THE MANAGEMENT OF COUGH
DEVELOPMENTS IN THE DIAGNOSIS AND TREATMENT OF THE COMMON TRIAD OF COUGH ETIOLOGIES
COUGH REFLEX HYPERSENSITIVITY AND ITS ASSOCIATION WITH COMMON ACUTE AND CHRONIC COUGH SYNDROMES
THE DEVELOPMENT OF NEW TREATMENTS FOR COUGH