Cough: An Interdisciplinary Problem, An Issue of Otolaryngologic Clinics

Author: Altman> Kenneth W.  

Publisher: Elsevier Health Sciences‎

Publication year: 2010

E-ISBN: 9781455700516

P-ISBN(Paperback): 9781437718492

Subject: R441.5 Cough, expectoration

Keyword: 耳鼻咽喉科学

Language: ENG

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Description

Both acute and chronic cough are responsible for a significant number of ambulatory medical visits annually. The recent comprehensive understanding that "e;cough is a reflection of underlying disease pays tribute to the multifactorial causes, as well recognition of the respiratory and upper digestive tract as a "e;physiologic unit. This publication highlights the advances made in managing cough and brings these to otolaryngology practitioners in a concise forum, as well as presenting issues of special interest to laryngologists such as paradoxical vocal fold motion, disordered breathing, irritable larynx, evolution of the vagus as a protective circuit, the importance of cough in deglutition, and surgical interventions. Some of the topics include: The cough reflex, sensory receptors, and neurogenic mediators; Mucus and mucins; Cough and Swallowing dysfunction; Cough due to asthma, cough-variant asthma, and nonasthmatic eosinophilic bronchitis; Occupational, environmental, and irritant induced cough; Pharmacologic management; Unexplained cough; Cough in the pediatric population; and Rhinogenic laryngitis, cough and the unified airway; among others.

Chapter

DIFFERENTIAL DIAGNOSIS FOR SUBACUTE COUGH

DIFFERENTIAL DIAGNOSIS FOR CHRONIC COUGH

CHRONIC BRONCHITIS

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS

COMMON CLINICAL PROFILE

SUMMARY

REFERENCES

Chapter 2. Afferent Nerves Regulating the Cough Reflex: Mechanisms and Mediators of Cough in Disease

CHEMICAL AND MECHANICAL STIMULI THAT INITIATE COUGHING

AFFERENT NERVES REGULATING THE COUGH REFLEX

RAPIDLY ADAPTING RECEPTORS

COUGH RECEPTORS

AFFERENT NERVE INTERACTIONS IN COUGH AND MECHANISMS OF COUGH IN DISEASE

SUMMARY

REFERENCES

Chapter 3. Mucus and Mucins

COMPOSITION OF MUCUS AND PHLEGM

MUCIN SECRETION AND MUCUS CLEARANCE

UPPER AND LOWER AIRWAY MUCUS

THERAPY FOR MUCUS CLEARANCE DISORDERS

SUMMARY

REFERENCES

Chapter 4. Cough and Swallowing Dysfunction

COUGH AND DYSPHAGIA

FUNDAMENTALS OF SWALLOW ASSESSMENT

FUNDAMENTALS OF SWALLOWING THERAPY

SUMMARY

REFERENCES

Chapter 5. Vocal Cord Dysfunction, Paradoxic Vocal Fold Motion, or Laryngomalacia? Our Understanding Requires an Interdisciplinary Approach

A HISTORICAL PERSPECTIVE

FOCUSING ON THE BIG PICTURE

WHAT DIAGNOSES ARE IN THE DIFFERENTIAL?

HOW DO WE ADDRESS COUGH?

DIFFERENCES AMONG PERIODIC OCCURRENCE OF LARYNGEAL OBSTRUCTION DISORDERS

ENDOSCOPIC EVALUATION

PARADOXIC VOCAL FOLD MOTION

VOCAL CORD DYSFUNCTION

INTERMITTENT ARYTENOID REGION PROLAPSE

THE THREE CATEGORIES OF PERIODIC OCCURRENCE OF LARYNGEAL OBSTRUCTION

VOCAL CORD DYSFUNCTION AND MASS PSYCHOGENIC ILLNESS

COUGH

HYPOTHESES FOR ORIGIN OF SOME LARYNGEAL DISORDERS

PULMONARY DIAGNOSTICS

VOCAL CORD DYSFUNCTION MANAGEMENT

SUMMARY

REFERENCES

Chapter 6. Evidence for Sensory Neuropathy and Pharmacologic Management

CLINICAL EVALUATION

TREATMENT OPTIONS

PHARMACEUTICALS FOR TREATMENT OF PVVN

SUMMARY

REFERENCES

Chapter 7. The Role of Voice Therapy in the Management of Paradoxical Vocal Fold Motion, Chronic Cough, and Laryngospasm

LARYNGOSPASM

PARADOXICAL VOCAL FOLD MOTION

CHRONIC COUGH

SUMMARY

APPENDIX 1. PRODUCT REFERENCES FOR RESISTANCE BREATHING DEVICES

REFERENCES

Chapter 8. Occupational, Environmental, and Irritant-Induced Cough

RESPIRATORY TRACT EFFECTS OF IRRITANTS

ALLERGEN VERSUS IRRITANT

ROLE OF ODOR

OCCUPATIONAL, ENVIRONMENTAL, AND IRRITANT-INDUCED COUGH

WORLD TRADE CENTER COUGH

EVOLUTION OF IRRITANT-INDUCED COUGH

IRRITANT-INDUCED COUGH, A TRPPATHY

REFERENCES

Chapter 9. Reflux and Cough

PATHOPHYSIOLOGY OF REFLUX

THE LES AND TRANSIENT LES RELAXATION

HOW DOES REFLUX AFFECT THE LARYNX AND UPPER AIRWAY?

COUGH: REFLUX OR REFLEX?

COUGH IN REFLUX: CLINICAL EVALUATION

TREATMENT

ALGINATE

COMPLICATIONS RELATED TO PPI THERAPY

PROKINETIC THERAPY

SURGERY

SUMMARY

REFERENCES

Chapter 10. Rhinogenic Laryngitis, Cough, and the Unified Airway

LARYNGEAL INVOLVEMENT IN THE UNIFIED AIRWAY

MUCUS, NEUROLOGIC REFLEXES, AND NEUROGENIC INFLAMMATION

DIAGNOSIS OF CHRONIC RHINOGENIC LARYNGITIS

MODEL FOR CHRONIC RHINOGENIC LARYNGITIS

SUMMARY

REFERENCES

Chapter 11. Cough Due to Asthma, Cough- Variant Asthma and Non-Asthmatic Eosinophilic Bronchitis

DEFINITION, DIAGNOSIS, AND PREVALENCE

EXHALED NITRIC OXIDE AS A SURROGATE FOR SPUTUM EOSINOPHILIA

PATHOGENESIS

DISEASE PROGRESSION

TREATMENT

SUMMARY

REFERENCES

Chapter 12. The Spectrum of Nonasthmatic Inflammatory Airway Diseases in Adults

CHRONIC BRONCHITIS

BRONCHIECTASIS

BRONCHIOLITIS IN ADULTS

REFERENCES

Chapter 13. Pharmacologic Management of Cough

ANTITUSSIVES

SUMMARY

ACKNOWLEDGMENTS

REFERENCES

Chapter 14. Assessing Efficacy of Therapy for Cough

SUBJECTIVE ASSESSMENTS OF COUGH

COUGH REFLEX SENSITIVITY TESTING

OBJECTIVE COUGH COUNTING

HEALTH-RELATED QUALITY OF LIFE

SELECTING PATIENT GROUPS FOR TESTING COUGH THERAPIES

CLINICAL TRIAL DESIGN

SUMMARY

REFERENCES

Chapter 15. Unexplained Cough in the Adult

UNEXPLAINED VERSUS IDIOPATHIC COUGH

HOW OFTEN IS CHRONIC COUGH UNEXPLAINED, AND WHAT ARE THE POTENTIAL EXPLANATIONS?

HOW SHOULD CLINICIANS AND RESEARCHERS APPROACH THE PROBLEM?

WHAT ARE THE PITFALLS IN MANAGEMENT, AND HAVE THEY BEEN AVOIDED?

HOW OFTEN WILL CHRONIC COUGH REMAIN TRULY UNEXPLAINED AFTER THE RECOMMENDED MANAGEMENT PROTOCOL HAS BEEN FOLLOWED?

WHAT ARE THE POTENTIAL PATHOGENIC MECHANISMS TO EXPLAIN THE TRULY REFRACTORY, UNEXPLAINED COUGH?

WHAT MANAGEMENT OPTIONS ARE AVAILABLE FOR THE TRULY REFRACTORY UNEXPLAINED COUGH?

SUMMARY

REFERENCES

Chapter 16. Cough in the Pediatric Population

EPIDEMIOLOGY DATA

PATHOPHYSIOLOGY

ETIOLOGIC FACTORS

EVALUATION OF CHILDREN WITH CHRONIC COUGH

REFERENCES

Chapter 17. Future Directions in Treating Cough

ACUTE AND CHRONIC COUGH—THE EXTENT OF THE PROBLEM

OPTIMIZING THE EXISTING PROTOCOLS FOR THE MANAGEMENT OF COUGH

DEVELOPMENTS IN THE DIAGNOSIS AND TREATMENT OF THE COMMON TRIAD OF COUGH ETIOLOGIES

COUGH REFLEX HYPERSENSITIVITY AND ITS ASSOCIATION WITH COMMON ACUTE AND CHRONIC COUGH SYNDROMES

THE DEVELOPMENT OF NEW TREATMENTS FOR COUGH

SUMMARY

REFERENCES

Index

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