Diagnostic Pathology of Infectious Disease

Author: Kradin> Richard L.  

Publisher: Elsevier Health Sciences‎

Publication year: 2010

E-ISBN: 9781455705986

P-ISBN(Paperback): 9781416034292

Subject: R51 infectious diseases

Keyword: 临床医学

Language: ENG

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Description

Diagnostic Pathology of Infectious Disease presents a comprehensive, organ-based approach to the effective and accurate diagnosis of infectious diseases. Dr. Richard L. Kradin covers the latest information on H1N1, as well as the use of immunohistochemical stains, PCR, Immunoperoxidase, and other molecular techniques for a current representation of the field. High-quality, full-color illustrations and differential diagnosis tables accompany each lesion so you can quickly identify and diagnose whatever you see. This reference is an invaluable tool for the accurate diagnosis of any infectious disease-from the common to the most challenging.Covers the latest techniques in immunohistochemistry and molecular genetics integrated throughout the text for comprehensive information on all investigative contexts relevant to ensuring diagnostic accuracy. Emphasizes the host responses critical in differential diagnosis to serve as a second opinion when non-infectious diagnoses mimic and confound the diagnosis of infection. Provides a complete visual guide to suspect lesions through superb, high-quality, full-color illustrations of key aspects of various diseases that facilitate the rapid identification of biopsy specimen. Presents contents organized by organ as opposed to pathogen to more effectively address diagnostic and management issues. Features tables that list differential diagnosis for each lesion for quick summaries of key points in problem areas. Highlights morphological charac

Chapter

Histochemical Stains

Immunohistochemical Methods

Molecular Diagnostics

In Situ Hybridization

REFERENCES

Chapter 3: The Biopsy in the Diagnosis of Infection:

Overview: The Biopsy

Approach to the Patient: General Concepts

Antimicrobial Therapy

Biopsy in the Immunocompromised Host

Timeline of Infection

Summary

REFERENCES

Chapter 4: Cytopathology of Infectious and Inflammatory Diseases

Introduction

Processing of Cytologic Samples for Infectious and Inflammatory Diseases

Culturing of Fine-Needle Aspirations for Microorganisms

Inflammatory Patterns and Associated Pathogens

Unusual Host Reactions to Infections in the Immunocompromised Patient

Cytodiagnosis of Viral Infections

Case 17: Intensive Care Unit Vocal Cord Lesion

Case 18: Is It Herpes or Molluscum?

Case 19: To Immunosuppress or Immunoenhance; That Is the Question!

Parasitic Disease in Cytology

Case 20: A Worm with the Wanderlust

Cases 21 and 22: Parasite Infections Seen in Postmortem Cytology

Conclusion

Sample Preparation and Staining for Diagnosis of Infectious and Inflammatory Diseases Including Pneumocystis

REFERENCES

Chapter 5: Ultrastructural Diagnosis of Infection

Introduction

Electron Microscopy Technique

Prions

Viral Infections

Bacterial Infections

Fungal Infections

Parasitic Infections

REFERENCES

Chapter 6: Ear, Nose, and Throat Infections

Bacterial Rhinosinusitis

Otitis Media

Tonsillitis

Peritonsillar Abscess

Rhinoscleroma

Actinomycosis

Botryomycosis

Syphilis

Tuberculosis

Leprosy

Oral Candidosis

Fungal Rhinosinusitis

Paracoccidioidomycosis

Sporotrichosis

Blastomycosis

Coccidioidomycosis

Cryptococcosis

Histoplasmosis

Rhinosporidiosis

Mucocutaneous Leishmaniasis

Epstein-Barr Virus

Herpes Simplex Virus

Human Papillomavirus

Human Immunodeficiency Virus

Mumps

REFERENCES

Chapter 7: Pulmonary Infections

Introduction

Handling Lung Biopsy Specimens

Pulmonary Injury in Infection

Microbes Associated with Bioterrorism

Pleural Infections

REFERENCES

Chapter 8: Cardiac Infections

Introduction

The Pathology of Infective Endocarditis

The Pathology of Myocarditis

The Pathology of Pericarditis

REFERENCES

Chapter 9: Infections of the Gastrointestinal Tract

Introduction

Infections of the Esophagus

Infections of the Stomach

Infections of the Small Bowel

Infectious Colitis

REFERENCES

Chapter 10: Liver and Bile Duct Infections

Viruses

Mycobacteria

Nonmycobacterial Bacteria

Spirochetes

Rickettsia

Fungi

Helminths

Protozoans

REFERENCES

Chapter 11: Infectious Lymphadenitis

Lymphadenitis of Viral or Possible Viral Etiology

Bacterial Lymphadenitis

Fungal Lymphadenitis

Protozoal Lymphadenitis

REFERENCES

Chapter 12: Infectious Diseases of the Bone Marrow and Spleen

Introduction

Patterns of Bone Marrow Response to Infections

Bone Marrow Features of Specific Infections

Infections Involving the Spleen

REFERENCES

Chapter 13: Bone Infections

Pathophysiology

Bacterial Osteomyelitis

Mycobacterial Osteomyelitis

Treponemal Osteomyelitis

Fungal Osteomyelitis

Mycetoma

Helminthic Osteomyelitis

Viral Osteomyelitis

Differential Diagnosis of Osteomyelitis

REFERENCES

Chapter 14: Infections of Joints, Synovium-Lined Structures, and Soft Tissue

Bacterial Arthritis

Fungal Arthritis

Viral Arthritis

Reactive Arthritis

Soft Tissue Infections

Myositis

Other Unusual Soft Tissue Infections

REFERENCES

Chapter 15: Genitourinary Infectious Disease Pathology

Genitourinary Cutaneous Infections

Kidney Infections

Bladder Infections

Infections of the Urethra

Infections of the Male Genitourinary System

REFERENCES

Chapter 16: Gynecologic Infections

Lower Genital Tract

Upper Genital Tract

REFERENCES

Chapter 17: Perinatal Infections

Ascending Infections

Hematogenously Spread Infections

Specific Infectious Organisms

Pregnancy-Associated Uterine Infections

Fetal and Congenital Infections

REFERENCES

Chapter 18: Infections of the Nervous System

Introduction

Acute Inflammatory Response

Chronic Inflammatory Response

Granulomatous or Predominantly Histiocytic Inflammatory Pattern

Minimal or No Inflammatory Response

REFERENCES

Chapter 19: Skin Infections

Diagnostic Approach

Bacterial Infections of the Skin

Viral Infections of the Skin

Fungal Skin Infections

Protozoal Infections

Helminth Infestations

Arthropod-Induced Diseases

Algal Infections

REFERENCES

Index

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