Diagnostic Surgical Pathology of the Head and Neck

Author: Gnepp> Douglas R.  

Publisher: Elsevier Health Sciences‎

Publication year: 2009

E-ISBN: 9781437719512

P-ISBN(Paperback): 9781416025894

Subject: R739.4 systemic tumor

Keyword: 基础医学

Language: ENG

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Description

This resource is the authoritative guide to problematic areas of the head and neck for the surgical pathologist. With particular emphasis placed on diagnostic problems and differential diagnosis in addition to coverage of more common diagnostically straightforward lesions, you'll get the most complete diagnostic picture possible. The updated second edition features new coverage and a more user-friendly layout. Expert Consult functionality allows you to access the entire contents of the book online, from any internet connection.Features the most comprehensive collection of head and neck pathology specimens in one reference for comparison with your findings.Covers rare as well as common diagnoses to help you identify even the most obscure disease entities.Provides clinicopathologic correlations throughout to give you all the information you need to formulate a complete diagnostic report.Emphasizes differential diagnosis and avoiding diagnostic pitfalls so you can overcome difficult diagnostic challenges.Covers FNA cytology, molecular genetic techniques, and immunohistochemistry to present the most compete diagnostic picture possible.Presents a brand-new chapter on specimen handling to ensure effective processing and reporting of head and neck specimens.Features more than 1700 full-color illustrations that capture the pathologic and cytopathologic appearances of the full range of common and rare neoplastic and non-neoplastic lesions.Allows you to access the entire contents of t

Chapter

Normal Anatomy

Pathologic Features of Preneoplasia of the Upper Aerodigestive Tract

Histologic Classification of Upper Aerodigestive Tract Preneoplastic Lesions

Classification of Intraepithelial Neoplasia

Correlation between Clinical and Histologic Classifications

Clinicopathologic Studies

Malignant Progression of Upper Aerodigestive Tract Preneoplastic Lesions

Intraoperative (Frozen-Section) Interpretation of Squamous Intraepithelial Neoplasia

Molecular Alterations in Carcinogenesis

Molecular Markers of Dysplasia

Biomarkers of Epithelial Maturation and Intraepithelial Maturation

References

Chapter 2: Squamous Cell Carcinoma of the Upper Aerodigestive System

Introduction

General Comments

Site-Specific Features

Squamous Cell Carcinoma: Unusual Variants

Concluding Remarks

References

Chapter 3: Nonsquamous Lesions of the Nasal Cavity, Paranasal Sinuses, and Nasopharynx

Anatomy and Histology

Inflammatory Disorders

Non-Neoplastic Lesions, Including Cystsand Hamartomas

Neoplasms

Miscellaneous Tumors

Metastatic Tumors

Acknowledgment

References

Chapter 4: Lesions of the Oral Cavity

Fibrous, Fibrohistiocytic, and Fibrovascular Lesions

Granuloma-like Mucosal Lesions with Giant Cells

Soft-Tissue Lesions with Bone or Cartilage

Noncalcified Soft-Tissue Tumors with Mixed or Ectopic Tissues

Soft-Tissue Cysts

Vascular Lesions

Tumors of Fatty Tissue

Neural Tumors

Muscle Tumors

Benign Epithelial Proliferations

Ulcerative and Blistering Mucosal Lesions

Pigmented Mucosal Lesions

References

Chapter 5: Nonsquamous Pathologic Diseases of the Hypopharynx, Larynx, and Trachea

Anatomic Relationships and Barriers or Pathways for Tumor Spread in the Hypopharynx and Larynx

Non-Neoplastic Diseases

Benign and Malignant Laryngeal Neoplasia

Acknowledgment

References

Chapter 6: Salivary and Lacrimal Glands

Development and Anatomy

Developmental Disorders

Sialadenitis, Sialolithiasis, and Sialadenosis

Primary Cystic Disease

Tumor-Like Lesions

Neoplasms

Special Techniques: Fine-Needle Aspiration Biopsy and Diagnosis

Tumors of the Lacrimal Gland and Sac

References

Chapter 7: Thyroid and Parathyroid Glands

Introduction

Thyroid Gland

Parathyroid Glands

References

Chapter 8: Soft-Tissue Tumors of the Head and Neck

Introduction

Benign and Reactive Fibroblastic, Fibrohistiocytic, and Myofibroblastic Tumors

Fibroblastic and Fibrohistiocytic Tumors of Intermediate (Borderline) Malignancy

Malignant Fibroblastic, Myofibroblastic, and Fibrohistiocytic Tumors

Benign and Malignant Tumors of Peripheral Nerve

Benign Adipocytic Tumors

Malignant Adipocytic Neoplasms

Benign and Reactive Vascular Tumors

Vascular Tumors of Intermediate (Borderline) Malignancy

Malignant Vascular Tumors

Tumors with Myogenous Differentiation

Miscellaneous Tumors

References

Chapter 9: Bone Lesions

Benign Bone Tumors

Osteosarcoma

Benign Cartilaginous Tumors

Chondrosarcoma

Chordoma

Fibro-osseous Lesions of the Craniofacial Skeleton

Giant Cell Lesions of the Craniofacial Skeleton

Acknowledgments

References

Chapter 10: Odontogenic Cysts and Tumors

Introduction

Odontogenic Cysts

Odontogenic Tumors

References

Chapter 11: Cysts of the Neck, Unknown Primary Tumor, and Neck Dissection

Anatomy

Cysts of the Neck

Unknown Primary Tumor

Neck Dissection

References

Chapter 12: Ear: External, Middle, and Temporal Bone

Introduction

External Ear

External Auditory Canal

Neoplasms of the Middle Ear and Temporal Bone

Inner Ear and Temporal Bone

References

Chapter 13: HemapHematopoietic Lesions

Introduction

Benign Lesions

Malignant Lesions

References

Chapter 14: Cutaneous Tumors and Pseudotumors of the Head and Neck

Introduction

Cutaneous Epithelial Neoplasms of the Head and Neck

Adnexal Neoplasms

Mesenchymal Tumors and Pseudotumors

Biologically Borderline Cutaneous Mesenchymal Tumors

Overtly Malignant Mesenchymal Neoplasms

Cutaneous Lymphoid Lesions of the Head and Neck

Melanocytic Proliferations

Conclusions

References

Chapter 15: Fine-Needle Aspiration Biopsy

Thyroid Gland

Salivary Glands

Oral Cavity

Odontogenic Cysts and Tumors

Selected Lesions of the Paranasal Sinuses and Nasopharynx

Soft-Tissue and Bone Tumors

References

Appendix I: Head and Neck Tumors: TNM Staging

Lip and Oral Cavity

Pharynx

Larynx

Nasal Cavity and Paranasal Sinuses

Major Salivary Glands (Parotid, Submandibular, and Sublingual)

Thyroid Gland

Soft-Tissue Sarcoma

Carcinoma of the Lacrimal Gland

Appendix II: Guidelines for the Dissection of Head and Neck Specimens

Introduction

General Remarks

Specific Features

References

Index

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