Chapter
Section I: PATHOPHYSIOLOGY OF NEONATAL SHOCK
Chapter 1. Etiology, Pathophysiology, and Phases of Neonatal Shock
DEFINITION AND STAGES OF NEONATAL SHOCK
Chapter 2. Autoregulation of Vital and Nonvital Organ Blood Flow in the Preterm and Term Neonate
REGULATION OF ARTERIAL TONE
INTERACTION OF AUTOREGULATION AND FUNCTIONAL ACTIVATION (METABOLIC BLOOD FLOW CONTROL)
BLOOD FLOW TO OTHER ORGANS
DISTRIBUTION OF CARDIAC OUTPUT IN THE HEALTHY HUMAN NEONATE
MECHANISMS GOVERNING THE REDISTRIBUTION OF CARDIAC OUTPUT IN THE FETAL ''DIVE'' REFLEX
DISTRIBUTION OF CARDIAC OUTPUT IN THE SHOCKED NEWBORN
Chapter 3. Definition of Normal Blood Pressure Range: The Elusive Target
NORMATIVE DATA FOR BLOOD PRESSURE IN NEONATES
ADJUNCTS TO BLOOD PRESSURE MEASUREMENT IN THE DIAGNOSIS OF COMPROMISED CIRCULATORY FUNCTION
CLINICAL FACTORS THAT MAY AFFECT BLOOD PRESSURE
Section II: DIAGNOSIS OF NEONATAL SHOCK
Chapter 4. Use of Organ Blood Flow Assessment in the Diagnosis and Treatment of Neonatal Shock
NEAR-INFRARED SPECTROSOPY
MAGNETIC RESONANCE IMAGING
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
STABLE XENON-ENHANCED COMPUTED TOMOGRAPHY
POSITRON EMISSION TOMOGRAPHY
Chapter 5. Functional Echocardiography in the Neonatal Intensive Care Unit
TWO-DIMENSIONAL IMAGING AND NORMAL CARDIAC STRUCTURE
WHAT CAN BE MEASURED WITH FUNCTIONAL ECHOCARDIOGRAPHY IN THE NICU?
PULMONARY ARTERY PRESSURE
MEASUREMENT OF BLOOD FLOW AND CARDIAC OUTPUT
MYOCARDIAL FUNCTION MEASURES
MYOCARDIAL FUNCTION: FUTURE DEVELOPMENTS
FUNCTIONAL ECHOCARDIOGRAPHY IN THE NICU IN SPECIFIC CLINICAL SITUATIONS
Chapter 6. Near-Infrared Spectroscopy and its Use for the Assessment of Tissue Perfusion in the Neonate
PRINCIPLES OF NEAR-INFRARED SPECTROSCOPY
NEAR-INFRARED SPECTROPHOTOMETERS
MEASUREMENTS OF PHYSIOLOGICAL VARIABLES
PHYSIOLOGICAL OBSERVATIONS USING NIRS
Chapter 7. Advanced Magnetic Resonance Neuroimaging Techniques in the Neonate with a Focus on Hemodynamic-related Brain Injury
MAGNETIC RESONANCE-COMPATIBLE NEONATAL INCUBATOR AND NEONATAL HEAD COIL
DIFFUSION-WEIGHTED IMAGING AND DIFFUSION TENSOR IMAGING IN THE NEONATAL BRAIN
QUANTITATIVE PROTON MRS OF THE NEONATAL BRAIN
PERFUSION MAGNETIC RESONANCE IMAGING OF NEONATAL BRAIN INJURY
FUNCTIONAL MAGNETIC RESONANCE IMAGING IN THE NEWBORN PERIOD
Section III: CLINICAL PRESENTATIONS OF NEONATAL SHOCK
Chapter 8. Clinical Presentations of Neonatal Shock: The VLBW Infant during the First Postnatal Day
DEFINITION OF HYPOTENSION AND ITS RELATIONSHIP TO LOW SYSTEMIC PERFUSION
THE TRANSITIONAL CIRCULATION IN THE VLBW INFANT
ASSESSMENT OF CARDIOVASCULAR COMPROMISE IN THE SHOCKED VLBW INFANT
SHORT- AND LONG-TERM EFFECTS OF CARDIOVASCULAR COMPROMISE/SHOCK IN THE VLBW INFANT
TREATMENT OPTIONS IN THE MANAGEMENT OF CARDIOVASCULAR COMPROMISE/SHOCK IN THE VLBW INFANT
PRESENTATION AND MANAGEMENT OF CARDIOVASCULAR COMPROMISE IN THE VLBW INFANT ON THE FIRST POSTNATAL DAY
Chapter 9. The Very Low Birth Weight Neonate with a Hemodynamically Significant Ductus Arteriosus during the First Postnatal Week
SIGNS AND SYMPTOMS OF PDA
CARDIOVASCULAR ADAPTATION TO PDA
EFFECTS OF HEMODYNAMICALLY SIGNIFICANT PDA ON BLOOD PRESSURE
EFFECTS OF HEMODYNAMICALLY SIGNIFICANT PDA ON ORGAN PERFUSION
CHANGES IN CARDIAC FUNCTION FOLLOWING PDA LIGATION
Chapter 10. The Preterm Neonate with Relative Adrenal Insufficiency and Vasopressor-resistant Hypotension
RELATIVE ADRENAL INSUFFICIENCY
VASOPRESSOR-RESISTANT HYPOTENSION
EVIDENCE OF RELATIVE ADRENAL INSUFFICIENCY IN SICK PREMATURE INFANTS
RAI, CARDIOVASCULAR INSUFFICIENCY, AND VASOPRESSOR-RESISTANT HYPOTENSION IN SICK PREMATURE INFANTS
CARDIOVASCULAR AND STRESS EFFECTS OF CORTOCOSTEROIDS AND PROPOSED MECHANISMS
Chapter 11. Clinical Presentations of Systemic Inflammatory Response in Term and Preterm Infants
PERINATAL INFLAMMATION, CORD BLOOD CYTOKINES, AND POSTNATAL HEMODYNAMIC VARIABLES
CLINICAL PRESENTATIONS OF NEONATAL SHOCK IN INFANTS WITH SYSTEMIC INFLAMMATORY RESPONSE SYNDROME
PULMONARY HYPERTENSION ASSOCIATED WITH SIRS
TREATMENT OF THE HYPOTENSIVE NEONATE WITH SIRS
Chapter 12. Shock in the Surgical Neonate
DEFINITION AND PHASES OF NEONATAL SHOCK
PATHOGENESIS OF NEONATAL SHOCK
DIAGNOSIS OF CIRCULATORY COMPROMISE AND SHOCK
SURGICAL NEONATES AND SHOCK
Section IV: WHERE IS THE EVIDENCE?
Chapter 13. Evidence-based Evaluation of the Management of Neonatal Shock
AVAILABLE EVIDENCE THAT NEONATAL HYPOTENSION AND/OR SYSTEMIC OR CEREBRAL BLOOD FLOW ABNORMALITIES AFFECT MORTALITY AND MORBIDITY, WITH SPECIAL INTEREST TO NEURODEVELOPMENTAL OUTCOME
AVAILABLE EVIDENCE THAT TREATMENT OF NEONATAL HYPOTENSION AND/OR SYSTEMIC OR CEREBRAL BLOOD FLOW ABNORMALITIES HAS AN IMPACT ON MORTALITY AND MORBIDITY, WITH SPECIAL INTEREST TO NEURODEVELOPMENTAL OUTCOME
Chapter 14. Prevalence of Congenital Heart Disease
IMPACT OF PRENATAL DIAGNOSIS
Chapter 15. Impact of Congenital Heart Disease and Surgical Intervention on Neurodevelopment
INTRAUTERINE FACTORS WHICH AFFECT DEVELOPMENT
PREOPERATIVE NEUROLOGICAL ABNORMALITIES IN BABIES WITH CONGENITAL HEART DISEASE
INTRAOPERATIVE FACTORS WHICH AFFECT NEUROBEHAVIORAL DEVELOPMENT AFTER CONGENITAL HEART SURGERY
NEURODEVELOPMENTAL OUTCOME AFTER SURGICAL REPAIR OF CONGENITAL HEART DISEASE
Chapter 16. Obstetric Management of Fetuses with Congenital Heart Disease
OBSTETRIC MANAGEMENT OF FETUSES WITH CONGENITAL HEART DISEASE
PRENATAL SCREENING FOR CARDIAC DEFECTS
INDICATIONS FOR FETAL ECHOCARDIOGRAPHY
MANAGEMENT FOLLOWING THE DIAGNOSIS OF AN ABNORMAL FETAL HEART
NON-CARDIAC STRUCTURAL ANOMALIES
CHROMOSOMAL ABNORMALITIES
Chapter 17. Fetal Cardiac Intervention
CATHETER-BASED TECHNIQUES
SURGICAL INTERVENTIONS FOR SPECIFIC LESIONS
CARDIOPULMONARY BYPASS FOR FETAL SURGERY
INTRA-AMNIOTIC ULTRASOUND FOR FETOSCOPY
Chapter 18. Impact of Prenatal Diagnosis on the Management of Congenital Heart Disease
CONTINUATION VERSUS TERMINATION OF PREGNANCY
IMPACT OF PRENATAL CARDIAC DIAGNOSIS ON THE PREVALENCE OF CONGENITAL HEART DISEASE
DOES A PRENATAL CARDIAC DIAGNOSIS ENHANCE NEONATAL SURVIVAL?
PRENATAL CARDIAC DIAGNOSIS AND IN UTERO MEDICAL THERAPY
PRENATAL CARDIAC DIAGNOSIS AND FETAL INTERVENTION
THE IMPACT OF PRENATAL CARDIAC DIAGNOSIS ON INFORMED CONSENT
Chapter 19. Neonatal Interventional Catheterizations
CREATION OF AN ATRIAL SEPTAL DEFECT
BALLOON ATRIAL SEPTOSTOMY
PULMONARY ATRESIA WITH INTACT SEPTUM
OTHER LESIONS WITH DECREASED PULMONARY BLOOD FLOW
COIL EMBOLIZATION OF VESSELS
NEONATAL ENDOVASCULAR STENTS
Chapter 20. Cardiac Surgery in the Neonate with Congenital Heart Disease
MECHANICAL CIRCULATORY SUPPORT IN THE NEONATE
Chapter 21. MRI Evaluation of the Neonate with Congenital Heart Disease
ASSESSMENT OF PULMONARY VASCULAR ANATOMY
ABNORMALITIES OF THE AORTIC ARCH
SYSTEMIC VENOUS ANOMALIES
PULMONARY VENOUS ANOMALIES
ABNORMALITIES OF THE AIRWAY
ASSESSMENT OF MYOCARDIAL VIABILITY AND PERFUSION
ASSESSMENT OF CARDIAC FUNCTION
MEASUREMENT OF BLOOD FLOW
ACCURACY OF MRI EVALUATION OF CONGENITAL HEART DISEASE
LIMITATIONS OF MRI IMAGING IN NEWBORNS
Chapter 22. The Twin-Twin Transfusion Syndrome: Evolving Concepts
CHARACTERISTIC FINDINGS AND MAKING THE DIAGNOSIS OF TWIN-TWIN TRANSFUSION SYNDROME
MECHANISM AND PATHOPHYSIOLOGY OF TWIN-TWIN TRANSFUSION SYNDROME
SPECTRUM OF CARDIOVASCULAR FINDINGS IN TWIN-TWIN TRANSFUSION SYNDROME
QUANTIFYING THE BURDEN OF CARDIOVASCULAR IMPAIRMENT IN TTTS
STRATEGIES FOR THE TREATMENT OF TWIN-TWIN TRANSFUSION SYNDROME
LONG-TERM ISSUES AND THE FUTURE
Hemodynamics and Cardiology: Neonatology Questions and Controversies
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