Chapter
Non-FDG-PET Radionuclides and Radiotherapy Target Delineation
Part II Principles of Imaging in Nuclear Medicine
Chapter 2 Principles of PET-CT Scanning
Clinical Imaging Protocols
Technical Aspects of PET Imaging
Part III PET-CT Fusion and Target Delineation
Chapter 3 Image Registration and Fusion Techniques
Radiotherapy Imaging Systems
Integrating PET Imaging into Radiation Treatment Planning
Image Registration Methods
Image Registration and Fusion Software Tools
Clinical Application of Image Registration and Fusion
Chapter 4 Biological Target Volume
VOLUMES FOR RADIATION TARGETING
LIMITATIONS OF CT-SIMULATION ALONE
POTENTIAL OF PET FOR BIOLOGICAL TARGET VOLUME
PET-CT SCANNING FOR TARGETING
IMPACT OF PET-CT ON TARGETS
DEFINING THE TARGET: CURRENT METHODS OF PET IMAGE SEGMENTATION
FUTURE RADIOTRACERS FOR TARGETING
Part IV Clinical Applications
Rationale for Use of PET or PET-CT in Head and Neck Cancer
Fusion Technique and Target Delineation
Problems Associated with PET-CT and Radiotherapy Target Delineation
Review of Studies Using PET-CT for Radiotherapy Planning
Use of Other Tracers in Radiotherapy Target Delineation for Head and Neck Cancer
Chapter 6 Esophageal Cancer
RATIONALE FOR THE USE OF PET AND PET-CT FOR ESOPHAGEAL CANCER
PET-CT SIMULATION AND TARGET VOLUME DELINEATION
PROBLEMS ASSOCIATED WITH PET-CT
Chapter 7 Rectal and Anal Cancers
Rationale for the Use of PET and PET-CT
Fusion Technique and Target Delineation
Problems Associated with PET-CT
Review of Studies Using PET-CT for Radiotherapy Planning
Chapter 8 Non-Small Cell Lung Cancer
Misregistration Due to Target Motion
PET-CT Changes in Target Volume Delineation
Retrospective Studies in PET-CT Fusion
Prospective Studies in PET-CT Fusion
Chapter 9 Small Cell Lung Cancer
FDG-PET in Staging of Small Cell Lung Cancer
Practical Aspects of Applying FDG-PET in Radiation Treatment Planning for Small Cell Lung Cancer
Chapter 10 Gynecologic Cancer
RATIONALE FOR USE OF PET AND PET-CT IN GYNECOLOGIC MALIGNANCIES
FUSION TECHNIQUE AND TARGET DELINEATION
PROBLEMS ASSOCIATED WITH PET-CT OF THE PELVIS
REVIEW OF STUDIES USING PET-CT FOR TREATMENT PLANNING IN GYNECOLOGIC MALIGNANCIES
OTHER GYNECOLOGIC SUBSITES
Chapter 11 Genitourinary Cancer
Rationale for Use of PET and PET-CT in Genitourinary Malignancies
Fusion Technique, Fiducial Markers, and Target Delineation
Problems Associated with PET-CT and Radiotherapy Target Delineation
PET-CT in Radiation Treatment Planning—Case Illustrations
Rationale for Use of PET and PET-CT for Lymphoma
Fusion Technique and Target Delineation
Pitfalls Associated with PET-CT
Review of Studies Using PET-CT for Radiotherapy Treatment Planning
PET-CT in Radiation Treatment Planning in Melanoma
Chapter 14 Pediatric Tumors
Special Issues in Children
Rationale for Use of PET or PET-CT in Pediatric Tumors
Possible Role of PET-CT in Radiotherapy Treatment Planning
Role of PET in Adaptive Therapy
Chapter 15 Central Nervous System Tumors
Energy Metabolism as Measured by 18F-fluorodeoxy-D-glucose (FDG)
Assessing Response to Therapy Using FDG-PET
Other Potential Markers for Diagnosis, Response, and Tumor Targeting Compared to FDG-PET Imaging
Grading and Prognosis: FDG-PET vs. Amino Acid Tracers
Other Markers of Tumor Proliferation Including DNA Synthesis, and Hypoxia as Related to Diagnosis, Grading, Outcome of High-Grade Gliomas, and Potential Targeting for Radiotherapy
Markers of DNA Biosynthesis 2-[11C]thymidine (TdR), 18F-3' deoxy-3' -fluorothymidine (FLT)
Part V Economic Considerations
Chapter 16 Economic Considerations of PET Scanning in Diagnosis, Staging, and Radiation Therapy Treatment Planning
Cost-Effectiveness of PET Scanning in the Workup and Diagnosis of Malignancies
Cost-Effectiveness of Incorporating PET Scanning in the Radiation Therapy Treatment Planning Process
PET-CT in Radiotherapy Treatment Planning
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