World Heart Research Yearbook. Volume 1 ( World Heart Research Yearbook )

Publication series :World Heart Research Yearbook

Author: Franz Halberg;R B Singh  

Publisher: Nova Science Publishers, Inc.‎

Publication year: 2017

E-ISBN: 9781536117714

P-ISBN(Paperback): 9781607418818

Subject: R54 in cardiac and vascular diseases (circulatory system)

Keyword: 心脏、血管(循环系)疾病

Language: ENG

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World Heart Research Yearbook. Volume 1

Chapter

REVASCULARIZATION IN ACUTE MYOCARDIAL INFARCTION USING PERCUSURGE IN DISTAL PROTECTION ACRONYM: RAPID

ABSTRACT

ABBREVIATIONS

INTRODUCTION

MATERIALS AND METHODS

Study Population

Study Protocol

Device Description

Procedure Description

Angiographic Analysis

Procedural Time

Study Endpoints

Assessment of Blood Flow

Thrombolysis in Myocardial Infarction (TIMI) Flow Grades

Device Success

Angiographic Success

Procedural Success

Periprocedural Adverse Events

No Reflow

Statistical Analysis

RESULTS

Baseline Demographic, Hemodynamic and Biochemical Characteristics

Angiographic and Lesion Characteristics and PCI Details

Periprocedural Adverse Event, Intracoronary Agents and Myocardial Flow Assessment

Time in Minutes Involved in Different Steps of the Procedure

DISCUSSION

Significance and Limitations of Our Study

CONCLUSION

REFERENCES

THE EFFECT OF AN ALPHA-LINOLENIC-ACID-RICH DIET ON THE CIRCADIAN RHYTHM OF CARDIAC EVENTS

ABSTRACT

INTRODUCTION

METHODS

Subjects and Study Design

Cardiac Events

Statistical Analysis

RESULTS

Timing of Events in Total Study Population

Dispersion of Events Along Quartiles of the Day

DISCUSSION

REFERENCES

MYOCARDIUM VIABILITY ASSESSED BY DELAYED CONTRAST-ENHANCED MAGNETIC RESONANCE IMAGING IN PATIENTS WITH SEVERE ISCHEMIC HEART FAILURE: A COMPARISON WITH THALLIUM SPECT AND DOBUTAMINE ECHOCARDIOGRAPHY

ABSTRACT

INTRODUCTION

MATERIALS AND METHODS

Patients

Echocardiography

201Tl SPECT Protocols

Cardiac MRI

Image Processing and Analysis

Echocardiographic Analysis

SPECT Image Analysis

MR Image Analysis

Statistical Analysis

RESULTS

Comparison of Viability Data

Follow-up Data

DISCUSSION

CONCLUSION

ACKNOWLEDGMENTS

REFERENCES

BENEFICIAL EFFECTS OF ADDITION OF FENOFIBRATE TO STATIN THERAPY IN PATIENTS WITH ACUTE CORONARY SYNDROME AFTER PERCUTANEOUS CORONARY INTERVENTIONS

ABSTRACT

INTRODUCTION

RESEARCH DESIGN AND METHODS

RESULTS

DISCUSSION

CONCLUSION

REFERENCES

EFFECTS OF SILDENAFIL IN CARDIOVASCULAR DISEASE

ABSTRACT

INTRODUCTION

CLINICAL OBSERVATIONS

EXISTING CLINICAL EVIDENCE

EXPERIMENTAL EVIDENCE

MECHANISMS

CONCLUSION

ACKNOWLEDGMENTS

REFERENCES

ASPIRIN RESISTANCE: NEED FOR A SPECIFIC, RAPID, POINT-OF-CARE ASSAY

ABSTRACT

INTRODUCTION

PLATELET PHYSIOLOGY

ARACHIDONIC ACID METABOLISM

STUDIES ON THE USE OF ASPIRIN AS AN INHIBITOR OF COX-1 ENZYMES

CLINICAL STUDIES ON THE USE OF ASPIRIN

ASPIRIN RESISTANCE

PREVALENCE OF ASPIRIN RESISTANCE

CLOPIDOGREL RESISTANCE

METHODOLOGIES

DISCUSSION

CONCLUSION

CONCLUSION

CIRCADIAN CARDIOLOGY

ABSTRACT

INTRODUCTION

THE INTERACTION OF GENES AND MEANS AND ADAPTATION

EVOLUTIONARY ASPECTS OF BIOLOGICAL FUNCTION RHYTHMICITY

EVOLUTIONARY ASPECTS OF DIET AND LIFESTYLE

CIRCADIAN

CLOCKS

STIMULUS TIMING CONTRIBUTES TO CHANCE OF DEATH VS SURVIVAL CIRCADIAN AMPLITUDE (AND PHASE ?) DIFFERENCE IN SUSCEPTIBILITY TO A CARDIAC DRUG, OUBAIN, OF TWO INBRED MOUSE STRAINS

TRIGGERS

CIRCADIAN RHYTHMS IN ISCHEMIC HEART DISEA

WHY MORNING IS SO RISKY?

THE POSSIBLE MECHANISMS INVOLVED

Relation to Plasma Endothelin-1

Fluctuation in Endothelial Function

Mechanism of Coronary Spasms

Mechanism of Diurnal Variation in Flow-Mediated Vasodilation

Heart Rate Variability and the Rate of Autonomic Change

CIRCADIAN RHYTHM IN MYOCARDIAL INFARCTION

Circadian Periodicity

PATHOGENESIS

CIRCADIAN VARIATION IN PLAQUE RUPTURE

Q-WAVE VERSUS NON-Q WAVE MI

CIRCADIAN DIFFERENCES IN THE SITE OF MYOCARDIAL INFARCTION AND IN THE INVOLVED CORONARY ARTERIES

CIRCADIAN RHYTHM AND SUDDEN CARDIAC DEATH

CIRCADIAN RHYTHM AND SCD

MECHANISMS UNDERLYING SUDDEN CARDIAC DEATH

Electrical Factors and Sudden Cardiac Death

Circadian Variation and Refractoriness

Circadian Variation and Repolarization

Circadian Variation in Serum Potassium and Plasma Catecholamine Levels

CIRCADIAN VARIATION IN CARDIAC EVENTS

CIRCADIAN RHYTHM AND STROKE

Monday Preference in Onset of Ischemic Stroke

Circadian Variation in Acute Ischemic Stroke

Loss of Circadian Rhythm of Blood Pressure Following Acute Stroke

Circadian Variation in the Timing of Stroke Onset

CIRCADIAN AND SEASONAL OCCURRENCE OF SUBARACHNOID AND INTRACEREBRAL HEMORRHAGE

CIRCADIAN VARIATION IN TRANSIENT ISCHAEMIC ATTACK

ONSET OF TRANSIENT ISCHAEMIC ATTACK/STROKE AND SLEEP CHARACTERISTICS

ONSET OF TRANSIENT ISCHAEMIC ATTACK/STROKE AND STROKE CHARACTERISTICS

NONPHARMACOLOGICAL TREATMENT

PHARMACOTHERAPY

CHRONOTHERAPEUTICS

TIME-TAILORED DRUGS

Selected Medications Exhibiting Circadian Variations in Pharmacokinetic and Pharmacodynamic Action

POTENTIAL ROLE OF CHRONOTHERAPY IN CARDIOVASCULAR DISEASES

Angiotensin Converting Enzyme Inhibitors

Calcium Channel Blockers

Aspirin

Beta Blockers

CONCLUSION

REFERENCES

DECREASED POTENTIAL OF MITOCHONDRIA MAY INCREASE RISK OF CARDIOVASCULAR DISEASE

NOT ONLY A COLD CLIMATE BUT ALSO A HOT CLIMATE CAN TRIGGER CARDIAC EVENTS

SCIENTIFIC SESSION NEWS FROM THE AMERICAN COLLEGE OF CARDIOLOGY, 54TH ANNUAL SCIENTIFIC SESSION, ORLANDO, MARCH 6-9, 2005. TRIALS COVER STEM CELLS, LOW LDL, MEDICATION EFFECTIVENESS

STEM CELLS IN ACUTE MYOCARDIAL INFARCTION

METALLOPROTEINASE INHIBITOR (PG116800) IN AMI

GENE THERAPY IN CORONARY ARTERY DISEASE

BRAVE-2 TRIAL WITH ABCIXIMAB

THE CACAF STUDY

CPAP FOR HEART FAILURE

CORONARY ARTERY DISEASE: RISK PROMOTERS, PATHOPHYSIOLOGY AND PREVENTION

TRENDS IN ATHEROSCLEROSIS RESEARCH

FOCUS ON ATHEROSCLEROSIS RESEARCH

CAN WILD WHOLE SEEDS PROTECT AGAINST CARDIOVASCULAR DISEASE?

REFERENCES

FRONTIERS IN WOMEN’S CARDIOVASCULAR HEALTH PREVENTION:WHAT HAVE WE LEARNED SO FAR?

INTRODUCTION

HORMONE REPLACEMENT THERAPY

Chapter 1: Proposed Mechanism for Estrogen’s Cardiovascular Protection

Chapter 2: Data from Randomized Control Trials: Why Placebo Matters

Chapter 3: Does the Type of HRT or the Method of Delivery Matter in Secondary Prevention? No

Chapter 4: Is There a Role of HRT in the Primary Prevention of CHD?

Chapter 5: Why Did ERT/HRT Fail? Unanswered Questions and Future Trials

OBESITY

DIET AND LIFESTYLE

What Does It All Mean?

DIETARY AND VITAMIN SUPPLEMENTS

Is There a Role for Anti-Oxidant Vitamin Supplements in the Primary or Secondary Prevention of CHD in Women?

Is There a Role for Folic Acid or Vitamin B6 in the Prevention of CHD in Women?

Is There a Role for Fish Oil (Omega-3 Fatty Acid) Supplementation in the Prevention of CHD in Women?

ASPIRIN USE IN WOMEN

The Debate over Aspirin in the Primary Prevention of CHD in Women

CHOLESTEROL AND INFLAMMATORY BIOMARKERS OF CHD IN WOMEN

The Optimal Lipid Levels in Women for the Prevention of CHD

Are There Other Markers of Inflammation that Are Predictive of CHD Events in Women?

DIAGNOSIS AND PROGNOSIS

Exercise Treadmill Testing – The Basics

Why Is Exercise Treadmill Testing Less Accurate in Women?

Does Perfusion Imaging Improve Diagnostic Accuracy in Women?

How Does Stress Echocardiography Compare with ETT?

Is There a Role for Electron Beam Tomography in the Detection of CAD in Women?

What Is the Prognostic Utility of Stress Testing in Women?

CONCLUSION

REFERENCES

MAGNETIC RESONANCE IMAGING METHODS INCARDIOVASCULAR IMAGING: EXPERIMENTAL AND CLINICAL APPLICATIONS WITH LIMITATIONS

INTRODUCTION

CMR SPECTROSCOPY AND IMAGING TECHNIQUES

CARDIAC MRI LOCALIZATION TECHNIQUES

CHEMICAL SHIFT IMAGING

EXPERIMENTAL CARDIAC MRI IMAGING APPLICATIONS

CLINICAL CARDIAC MRI IMAGING APPLICATIONS

Magnetic Resonance Angiography

Myocardial-Viability Assessment: Delayed Contrast Enhancement

Myocardial Contractile Function

Radiofrequency Tagging and Phase Tracking Contrast

Cine MRI Technique

Image-Guided Catheter Placement

Coronary MR Angiography

Plaque Imaging and Characterization

QUANTIZATION AND CHARACTERIZATION OF PLAQUE

Myocardial-Perfusion Imaging

Time Series MRI as 31Phosphorus Stress Test

Sodium-23 MRI of Myocardial Sarcolemmal Integrity

Myocardial Intracellular Lipid Content

IMAGING APPLICATIONS IN FUTURE

Diffusion Weighted Myocardial Imaging

Nanoparticle Targeted Contrast Agents

CARDIAC 17OXYGEN MRI IMAGING

MRI SUSCEPTIBILITY IMAGING

MOLECULAR AND METABOLIC IMAGING APPLICATIONS

Localized Carbon-13 MR Spectroscopy

Cardiac TCA Cycle Kinetics

LIMITATIONS AND FUTURE OF CARDIAC MR

Cardiac Spectroscopic Imaging

CONCLUSION

REFERENCES

PHYSICAL PARAMETERS ARE GOOD PREDICTORS OF CARDIORESPIRATORY FITNESS IN MALE COLLEGE STUDENTS OF INDIA

ABSTRACT

INTRODUCTION

METHODS

Selection of Subjects

Preparation of Subjects [7]

Determination of Physical Fitness Index

Statistical Analysis

RESULTS

DISCUSSION

REFERENCES

HUMAN CORONARY ARTERY LESIONS:MAGNETIC RESONANCE IMAGING, NMR SPECTROSCOPY, HISTOPATHOLOGY AND OXIDATIVE STRESS MARKERS

ABSTRACT

INTRODUCTION

MATERIALS AND METHODS

Ex Vivo MRI and High-Resolution NMR Spectroscopy of Coronary Plaque

Coronary Wall and Plaque Measurements

Histology of Plaque

Oxidative Stress Markers

RESULTS

Ex Vivo MRI of Coronary Artery Endarterectomy Specimens

Histopathology

High-Resolution NMR Spectroscopy of Coronary Plaques

Oxidative Stress Markers

DISCUSSION

Multicontrast MR Plaque Imaging

Ex Vivo MR Imaging of Human Coronary Arteries and Aorta Histopathology Correlation

Sensitivity and Specificity of Coronary MRI (Stenoses: > 50%)

Coronary Plaque Lipids with High Resolution NMR Spectroscopy

Coronary Oxidative Stress Markers

Limitation of This Study

CONCLUSION

ACKNOWLEDGMENTS

REFERENCES

HUMAN CAROTID ARTERY:SEGMENTATION METHODS IN ATHEROSCLEROSIS IMAGING

ABSTRACT

INTRODUCTION

THEORY

Vascular Image Segmentation

Deformable Models as SNAKES or Active Contours

Dynamic Force Formulation

Interpretation of Features from Segmentation

Classification vs. Representation

Classification vs. Representation

Quantitative Analysis of Segmented Images and Algorithms

Vasculature Assessment (Object Extraction) Algorithm

Artery Visualization and Suppression of Overlapping Veins

SNAKES Algorithm

Tracking the Carotid Aorta

Dynamic Programming Algorithm

CONTRAST ENHANCEMENT METHODS

Object Delineation

Manual Delineation

Automated Delineation

Simulated Scenes

Simulated Scenes

Contour Delineation

Object Recognition

3D Reconstruction and 3D Rendering Analysis

MATERIALS AND METHODS

Image Acquisition for Carotid Artery Bifurcation

Multicontrast Protocol

T1 Parametric Contrast Method

T2 Parametric Imaging for Segmentation and Quantification of Plaque Components

Supervised Semi-automated Parametric Color coded Segmentation Method

3D Reconstruction Display

RESULTS

T1 Parametric Contrast

T2 Parametric Contrast

Multiparametric Contrast

3D Reconstruction

Volume Rendering and 3D Display

Deformable Models and SNAKES for Wall Thickness Segmentation

Evaluation of Segmentation

Color-coded Feature Maps

Plaque Voluming

DISCUSSION

CONCLUSION

REFERENCES

LARGER CIRCADIAN AMPLITUDE OF HEART RATE ASSOCIATED WITH ACTIVE PRAYER IN HINDU INDIANS IN ASIA

ABSTRACT

INTRODUCTION

SUBJECTS AND METHODS

RESULTS

DISCUSSION AND CONCLUSION

REFERENCES

SEPARATE CARDIOVASCULAR DISEASE RISKS:CIRCADIAN HYPER-AMPLITUDE-TENSION (CHAT) AND AN ELEVATED PULSE PRESSURE

ABSTRACT

INTRODUCTION

SUBJECTS AND METHODS

RESULTS

DISCUSSION

REFERENCES

HOME C-ABPM FOR PREVENTIVE AND CURATIVE HEALTH CARE AND TRANSDISCIPLINARY SCIENCE

ABSTRACT

BACKGROUND

INTER- AND INTRA-INDIVIDUAL VARIABILITY

CONSEQUENCES OF SPOTCHECKS

SPHYGMOCHRONS

PRACTICABILITY

CHRONOMICS FOR MEDICAL AND OTHER SCIENCE

EPILOGUE

REFERENCES

THE POTENTIAL BENEFITS IF SAPONIN FROM CANADIAN-GROWN FENUGREEK (TRIGONELLA FOENUM-GRAECUM L.) IN MODIFYING CHOLESTEROL STATUS

ABSTRACT

INTRODUCTION

MATERIALS AND METHODS

Fenugreek Seed

Extraction of Fenugreek Seeds

Cholesterol-Binding Capacity

Bile Acid-Binding Capacity

RESULTS

DISCUSSION

ACKNOWLEDGMENT

REFERENCES

CAN WILD WHOLE SEEDS PROTECT AGAINST CARDIOVASCULAR DISEASE?

REFERENCES

REDUCING CARDIOVASCULAR DISEASE RISK THROUGH MANAGEMENT OF HYPERGLYCEMIA: PROSPECTS AND PITFALLS

ABSTRACT

INTRODUCTION

METFORMIN

THIAZOLIDINEDIONES

EXOGENOUS INSULIN ADMINISTRATION AND CARDIOVASCULAR RISK IN TYPE 2 DIABETES MELLITUS

CONCLUSION

REFERENCES

PREVENTION OF ISCHEMIC HEART DISEASE IN PATIENTS WITH DIABETES MELLITUS

ABSTRACT

PHARMACOLOGICAL TREATMENT OF DIABETIC PATIENTS WITHOUT CARDIOVASCULAR DISEASE (PRIMARY PREVENTION)

Glycemic Control

Lipid Lowering Therapy

Blood Pressure Control

Antithrombotic Therapy

PHARMACOLOGICAL TREATMENT OF DIABETICS WITH CORONARY ARTERY DISEASE (SECONDARY PREVENTION)

Beta-Blocker Therapy

Lipid Lowering Therapy

Treatment with ACE Inhibitors

Antithrombotic Therapy

PHARMACOLOGICAL CARDIOVASCULAR PREVENTION AND DIAGNOSIS OF NEW ONSET DIABETES

USE OF CARDIOVASCULAR PREVENTION INTERVENTIONS IN DIABETIC PATIENTS IN THE REAL WORLD

CONCLUSION

REFERENCES

ETHNIC DIFFERENCES IN DIET AND LIFESTYLE FACTORS AND AMBULATORY BLOOD PRESSURE AND HEART RATE IN ASIAN INDIANS LIVING IN UNITED STATES

REFERENCES

ACUTE CORONARY SYNDROME:A PROGRESSION OF PRE-METABOLIC SYNDROME

REFERENCES

CONTINUED 7-DAY/24-HOUR MONITORING REQUIRED IN (MESOR-) HYPERTENSION AND OTHER VVDS (VASCULAR VARIABILITY DISORDERS)

ABSTRACT

INTRODUCTION

CASE REPORT AND METHODS

COMMENTS

EPILOGUE

REFERENCES

MODIFYING EFFECT OF PUNICA GRANATUM FLOWERS ON LIPIDS AND LIPIDS-METABOLIZING ENZYMES STATUS IN STREPTOZOTOCIN INDUCED DIABETIC RATS

ABSTRACT

INTRODUCTION

MATERIALS AND METHODS

Chemicals

Animals

Preparation of Ethanolic Extract of Punica Granatum Flowers

Induction of Diabetes Mellitus

Experimental Design

Biochemical Estimations

Statistical Analysis

RESULTS

DISCUSSION

REFERENCES

BODY COMPOSITION AND CARDIO-VASCULAR STATUS OF INDIAN SCHOOL GOING GIRLS

ABSTRACT

INTRODUCTION

MATERIALS AND METHODS

Statistical Analysis

RESULTS

DISCUSSION

CONCLUSION

ACKNOWLEDGMENT

REFERENCES

ASSOCIATION OF INCREASED MORTALITY WITH UNDERWEIGHT, OVERWEIGHT AND OBESITY AMONG URBAN DECENDENTS IN NORTH INDIA, DYING DUE TO VARIOUS CAUSES

ABSTRACT

INTRODUCTION

MATERIAL AND METHODS

Statistical Analysis

RESULTS

DISCUSSION

ACKNOWLEDGMENTS

REFERENCES

PLASMA BRAIN NATRIURETIC PEPTIDE – AN INDEPENDENT PREDICTOR OF MORTALITY AND REHOSPITALIZATION IN CONGESTIVE HEART FAILURE – A META-ANALYSIS

ABSTRACT

INTRODUCTION

MATERIAL AND METHODS

Design

Literature Search

Validity Assessment

Data Abstraction

Analysis

RESULTS

DISCUSSION

REFERENCES

FALSE TENDON INDUCED SUBAORTIC HYPERTROPHY — A NEW VARIANT OF HYPERTROPHIC CARDIOMYOPATHY?

ABSTRACT

INTRODUCTION

METHODS

RESULTS

DISCUSSION

REFERENCES

CARDIOVASCULAR DISEASE AND ERECTILE DYSFUNCTION: THE EVOLVING ROLE OF PHOSPHODIESTERASE-5-INHIBITORS

INTRODUCTION

ENDOTHELIAL DYSFUNCTION

ERECTILE DYSFUNCTION AS A SURROGATE MARKER FOR CARDIOVASCULAR DISEASE

PHOSPHODIESTERASE INHIBITORS

USE OF PDEIS IN PATIENTS WITH CVD HEART FAILURE

PULMONARY HYPERTENSION

DIABETES

CORONARY ARTERY DISEASE

CONCLUSION

REFERENCES

INDEX

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