Chapter
2 History of Psychotic Depression
Differentiating melancholy
Swimming in and out of view
The DSM series: psychotic depression as a subclass of ‘‘major depression’’
Psychotic depression as an independent disease
3 Diagnosis in Psychotic Depression
Problems with the DSM definition of psychotic depression
Issues with the ICD-10 description of psychotic depression
The behaviors of psychotic depression
Who gets psychotic depression and the risks
Schizoaffective or psychotic depression?
Delusional disorder versus psychotic depression
A typology of psychotic depression
Melancholic psychotic depression
Psychosis-dominant depression
Catatonic psychotic depression
Psychotic-equivalent depression
Tardive psychotic depression
Drug-induced and hormone-induced psychotic depression (including postpartum psychosis)
Coarse brain disease psychotic depression
Pseudopsychosis, or false psychotic depression
Psychotic versus nonpsychotic major depression
Depression-induced anxiety disorders
4 Patients’ Experience of Illness
5 Treatment in Historical Perspective
An illness that awaits good news
Antimelancholic medication: Chlorpromazine
Antimelancholic medication: The tricyclic antidepressants
Antimelancholia: new treatment possibilities
6 Treatment: Pitfalls and Pathways
Treatment versus management
Common pitfalls in studying treatment
Rating scale shortcomings
Places for treatment and ECT
A common path to treatment
7 Treatment: ECT, Medications, and More
Electroconvulsive therapy
Prevention of recurrence after ECT
Safety of ECT versus antipsychotic drugs
Antimelancholic drugs alone
Antidepressant-induced mania
Tricyclics with triiodothyronine in females
Antipsychotic drugs alone
Antipsychotic-antimelancholic combination
Adding a third drug to antimelancholic-antipsychotic
Monoamine Oxidase Inhibitors (MAOIs)
Serotonin Reuptake Inhibitors (SRIs, SSRIs)
Combination antipsychotic-fluoxetine and -paroxetine
Other SSRIs in combination with antipsychotics
Mirtazapine, Nefazodone, Topiramate
Repetitive Transcranial Magnetic Brain Stimulation (TMS)
Surgery, deep brain stimulation, vagal nerve stimulation
8 Treatment by Type of Psychotic Depression
Melancholic psychotic depression
Preventing recurrence of the melancholic type
Psychosis-dominant depression
Bipolar mixed state subtype
Method of antipsychotic management
Treating severe anxiety disorder
Preventing recurrence of psychosis-dominant type
Catatonic psychotic depression
Psychotic-equivalent depression
Tardive psychotic depression
The lithium method for tardive psychosis
The carvedilol method for tardive psychosis
The clozapine method for tardive psychosis
The antipsychotic method for tardive psychosis
Drug-induced and hormone-induced psychotic depression
Psychotic depression in epilepsy and epileptic psychotic depression – other coarse brain disease
Untyped, Unknown, Unclear
Residual depressive symptoms and PTSD
Appendix 1 Summary Guide to Psychiatric Concepts
History of illness and mental status examination
Laboratory tests in psychiatry
Appendix 2 Summary Guide to Psychotropic Medication and Treatment
Antipsychotic tranquilizers
Dopamine blockers that rarely cause drowsiness
Dopamine blockers that often cause drowsiness
Mixed dopamine blockers – prefrontal inhibitors
Antimelancholic antidepressants
Miscellaneous psychotropics
Benzodiazepine tranquilizers
Psychotic Depression
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