Cover

Title Page

Copyright Page

Contents

Preface

1 Introduction

References

2 Nanomaterials

2.1 Physical Properties of Nanomaterials

2.1.1 Thermodynamic Properties: Melting Point Depression and Superheating

2.1.2 Optical Properties

2.1.3 Magnetism

2.2 Nanomaterials: An Overview

2.2.1 Organic Nanoparticles

2.2.2 Inorganic Nanoparticles

References

3 Promising Applications in Medicine

3.1 Diagnostics

3.1.1 X-Ray Computed Tomography

3.1.2 Photoacoustic Imaging

3.1.3 Positron Emission Tomography

3.1.4 Magnetic Resonance Imaging

3.1.5 Raman-Based Diagnostics

3.2 Therapy

3.2.1 Chemotherapy

3.2.2 Hyperthermia

3.2.3 Radiotherapy

References

4 Interactions of Nanomaterials with Biological Systems

4.1 Cellular Level (in vitro)

4.1.1 Cellular Uptake and Intracellular Fate

4.1.2 Physio-Chemical Dependence of Nanomaterials Uptake

4.1.3 Cytotoxicity

4.2 Body Level (in vivo)

4.2.1 Blood Circulation

4.2.2 Immune/Inflammatory Response

4.2.3 Metabolism (RES, Degradation, Excretion and Persistence)

References

5 Nanomaterials in the Market or in the Way of

5.1 Approval Pipeline (FDA and EMA)

5.2 Nanotherapeutics

5.3 Nanodiagnostics

References

6 Avoiding the Persistence of Metal Nanomaterials

6.1 Ultrasmall-in-Nano Approach

6.2 Porphyrin-Based Nanomaterials

References

7 Conclusions and Perspectives

References

Index

EULA