Joint Involvement and Synovial Histopathology in BD
( Behcet's Disease )
Publication series ： Behcet's Disease
Author： Yuki Nanke and Shigeru Kotake
Publisher： IntechOpen
Publication year： 2017
E-ISBN: INT6588468078
P-ISBN(Paperback): 9789535132257
P-ISBN(Hardback): 9789535132264
Subject： R6 Surgery
Keyword： 外科学
Language： ENG
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Joint Involvement and Synovial Histopathology in BD
Description
Behcet’s disease (BD) is a polysymptomatic and recurrent systemic vasculitis with a chronic course and unknown cause. Joint involvement in BD is common. Arthritis and arthralgia in BD are known to be the most common rheumatologic findings. Arthropathy in BD is monoarthritis or asymmetrical oligoarthritis affecting larger joints, and it is usually acute or recurrent with a self-limiting course. Bone deformity and destruction are rare. Autoantibodies are typically negative, and the presence of anti-CCP antibodies at high titers favors a diagnosis of rheumatoid arthritis (RA). Although joint involvement is clinically well recognized, few histologic studies have been reported. In this chapter, we focused on the synovitis and synovial histopathology in BD.
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