RNA Interference Technology — Applications and Limitations
( RNA Interference )
Publication series ： RNA Interference
Author： Devi Singh Sarika Chaudhary Rajendra Kumar Preeti Sirohi5
Publisher： IntechOpen
Publication year： 2016
E-ISBN: INT6063161760
P-ISBN(Paperback): 9789535122722
P-ISBN(Hardback): 9789535122722
Subject： R394 medical genetics
Keyword： 医学遗传学
Language： ENG
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RNA Interference Technology — Applications and Limitations
Description
RNA interference (RNAi), an evolutionarily conserved mechanism triggered by double-stranded RNA (dsRNA), causes gene silencing in a sequence-specific manner. RNAi evolved naturally to mediate protection from both endogenous and exogenous pathogenic nucleic acids and to modulate gene expression. Multiple technological advancements and precision in gene targeting have allowed a plethora of potential applications, ranging from targeting infections in crop plants to improving health in human patients, which have been reviewed in this chapter.
Chapter