Modern Technologies for Timely Detection and Differential Diagnosis of Gastric Cancer
( New Aspects in Molecular and Cellular Mechanisms of Human Carcinogenesis )
Publication series ： New Aspects in Molecular and Cellular Mechanisms of Human Carcinogenesis
Author： Vladimir Levkin Nina Gagarina Sergey Kharnas Gaziyav Musaev5
Publisher： IntechOpen
Publication year： 2016
E-ISBN: INT5982662540
P-ISBN(Paperback): 9789535122531
P-ISBN(Hardback): 9789535122531
Subject： R73 Oncology
Keyword： 肿瘤学
Language： ENG
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Modern Technologies for Timely Detection and Differential Diagnosis of Gastric Cancer
Description
The diagnostic potentialities of laser spectro- and videofluorescence endoscopy, complex transabdominal US examination, dynamic multihelical computed tomography (MHCT) with the possibility of constructing multiplanar reformations, and virtual gastroscopy were studied with a view to diagnosing gastric cancer (GC). It was established that laser spectral fluorescence with the drug Alasens (5-aminolevulinic acid) is a highly revealing method for diagnosis and differential diagnosis of GC. The sensitivity of the method is 96%, and its specificity is 78%. Well-defined videofluorescence was noted in 91.3% of patients with GC. The possibility of detecting cancer with complex trans-ultrasonography in the pyloroantral division and in the lower third of the body of the stomach constitutes 95.6% attaining absolute values in T3 and T4. Dynamic MHCT allows 97% detection of GC attaining absolute values, beginning with T2 invasion depth; tumor localization is irrelevant. Comparative visual assessment of the quality of a virtual image and conventional video esophagogastroduodenoscopy (EGDS) was made. The study demonstrated a sufficiently high level of virtual images whose quality was not inferior to that of conventional images in intraluminal tumor growth. The indications for the application of this technique require further specification.
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