Energy-Dependent Mechanisms of Cholinergic Neurodegeneration ( Neurochemistry )

Publication series ： Neurochemistry

Author： Agnieszka Jankowska-Kulawy Anna Ronowska and AndrzejSzutowicz  

Publisher： IntechOpen‎

Publication year： 2014

E-ISBN: INT5707458339

P-ISBN(Paperback): 9789535112372

P-ISBN(Hardback):  9789535112372

Subject： R74 Neurology and Psychiatry

Keyword： 神经病学与精神病学

Language： ENG

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Energy-Dependent Mechanisms of Cholinergic Neurodegeneration

Chapter

Chapter 13 Energy-Dependent Mechanisms of Cholinergic Neurodegeneration

1. Introduction

2. Brain energy metabolism

3. Cholinergic neurons and their role in central nervous system

4. Selective vulnerability of cholinergic neurons

5. Alzheimer’s disease

6. Hypometabolism in Alzheimer’s disease

7. Pivotal role of acetyl-CoA

8. Acute and chronic neurotoxicity

9. Amyloid-β toxicity

10. Zinc neurotoxicity

11. NO excess

12. Thiamine deficiency

13. Glia and neurotoxicity

14. Conclusions

Author details

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