Chapter 12 Review of the Biological and Health Effects of Aflatoxins on Body Organs and Body Systems

1. Introduction

2. Absorption, distribution, metabolism, excretion and mechanisms of action of aflatoxins

2.1. Effect of aflatoxins on mitochondrial DNA

2.2. Effect of aflatoxins on mitochondrial structure

2.3. Role of glutathione in detoxification of aflatoxins and their metabolites

2.4. The role of cytoplasmic reductase in detoxification of AFB1

2.5. Effect of aflatoxins on protein synthesis

2.6. Role of aflatoxins in cancer

3. Health effects of aflatoxins on human and animals (Aflatoxicosis)

4. Biological effect of aflatoxins on the body organs and body systems

4.1. Role of aflatoxins in hepatic injury and other body organs and tissues

4.2. Effect of aflatoxins on the central nervous system

4.3. Effect of aflatoxins on the gastrointestinal tract (GIT)

4.4. Effect of aflatoxins on the respiratory system

4.5. Effect of aflatoxins on the cardiovascular system, blood and blood cells

4.6. Effect of aflatoxins on the blood and blood cells

4.7. Effect of aflatoxins on the urinary system

4.8. Effect of aflatoxins on the endocrine system

4.9. Effect of aflatoxins on the reproductive system

5. Effect of aflatoxins on the immune system

6. Conclusion

Author details

References