The Amyloidogenic Pathway Meets the Reelin Signaling Cascade: A Cytoskeleton Bridge Between Neurodevelopment and Neurodegeneration ( Understanding Alzheimer's Disease )

Publication series ： Understanding Alzheimer's Disease

Author： Daniel A. Bórquez Ismael Palacios and Christian González-Billault  

Publisher： IntechOpen‎

Publication year： 2013

E-ISBN: INT4600454038

P-ISBN(Paperback): 9789535110095

P-ISBN(Hardback):  9789535110095

Subject： R741 Neurology

Keyword： 神经病学

Language： ENG

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The Amyloidogenic Pathway Meets the Reelin Signaling Cascade: A Cytoskeleton Bridge Between Neurodevelopment and Neurodegeneration

Chapter

Chapter 3 The Amyloidogenic Pathway Meets the Reelin Signaling Cascade: A Cytoskeleton Bridge Between Neurodevelopment and Neurodegeneration

1. Introduction

2. Reelin in neurodevelopment

3. Reelin in the adult brain

4. Animals models for neuropsychiatric diseases

5. Cytoskeletal abnormalities in Alzheimer´s disease

5.1. Tau protein and neurofibrillary tangles

5.2. Cofilin and actin-rods

6. Is the AD-associated Reelin reduction a major factor involved in the neuronal cytoskeleton pathology?

6.1. Reelin reduction in AD brains

6.2. Cytoskeletal pathologies and Reelin signaling

References

Author details

References

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