Progenitor/Stem Cell Engineering for Treatment of Ischemic Heart Diseases: Therapeutic Potentials and Challenges ( Ischemic Heart Disease )

Publication series ： Ischemic Heart Disease

Author： Yuliang Feng Yigang Wang and Shi-Zheng Wu  

Publisher： IntechOpen‎

Publication year： 2013

E-ISBN: INT5614753517

P-ISBN(Paperback): 9789535109938

P-ISBN(Hardback):  9789535109938

Subject： R54 in cardiac and vascular diseases (circulatory system)

Keyword： 心脏、血管（循环系）疾病

Language： ENG

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Progenitor/Stem Cell Engineering for Treatment of Ischemic Heart Diseases: Therapeutic Potentials and Challenges

Chapter

Chapter 10 Progenitor/Stem Cell Engineering for Treatment of Ischemic Heart Diseases: Therapeutic Potentials and Challenges

1. Introduction

1.1. Treatment for ischemic heart diseases: State-of-the-art

2. Proper cell sources

3. Engineering approach

3.1. Scaffold free tissue construct

3.2. Construction of myocardial tissue/heart using decellularized native tissue

3.3. Porous scaffolds

3.4. Biological and synthetic polymers

4. Progenitor/stem cell niche engineering

4.1. Matrix rigidity

4.2. Exosome secretion

5. Conclusions

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