Polylipid Nanoparticle, a Novel Lipid-Based Vector for Liver Gene Transfer ( Gene Therapy - Tools and Potential Applications )

Publication series ： Gene Therapy - Tools and Potential Applications

Author： Yahan Fan and Jian Wu

Publisher： IntechOpen‎

Publication year： 2013

E-ISBN: INT5019454270

P-ISBN(Paperback): 9789535110149

P-ISBN(Hardback): 9789535110149

Subject： R394 medical genetics

Keyword：医学遗传学

Language： ENG

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Polylipid Nanoparticle, a Novel Lipid-Based Vector for Liver Gene Transfer

Chapter

Chapter 5 Polylipid Nanoparticle, a Novel Lipid-Based Vector for Liver Gene Transfer

1. Introduction

2. Nanoparticle carriers for drug or gene delivery

3. Liver-specific gene delivery

4. Polylipid nanoparticle-mediated liver gene delivery

5. Preclinical trials for proof of the concept

6. Challenges in scaling-up and moving towards clinical applications

7. Conclusion and prospectives

Abbreviations used in the chapter

Author details

References

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