Induction of Autophagy by Anthrax Lethal Toxin ( Autophagy - A Double-Edged Sword - Cell Survival or Death? )

Publication series ： Autophagy - A Double-Edged Sword - Cell Survival or Death?

Author： Aiguo Wu Yian Kim Tan and Hao A. Vu  

Publisher： IntechOpen‎

Publication year： 2013

E-ISBN: INT5085555873

P-ISBN(Paperback): 9789535110620

P-ISBN(Hardback):  9789535110620

Subject： Q2 Cytobiology

Keyword： 细胞生物学

Language： ENG

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Induction of Autophagy by Anthrax Lethal Toxin

Chapter

Chapter 15 Induction of Autophagy by Anthrax Lethal Toxin

1. Introduction

2. Anthrax lethal toxin induces autophagy

2.1. Cells and induction of autophagy

2.2. Acridine orange staining showed increased Acidic Vacuoles (AVO)

2.3. Increased GFP-LC3 punctuate when cells were treated with LT

2.4. Conversion of LC3-I to LC3-II

2.5. Autophagy inhibitor may increase cell death

3. Discussion

Author details

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