Chromatin Remodelling During Host-Bacterial Pathogen Interaction ( Chromatin Remodelling )

Publication series ： Chromatin Remodelling

Author： Yong Zhong Xu Cynthia Kanagaratham and Danuta Radzioch  

Publisher： IntechOpen‎

Publication year： 2013

E-ISBN: INT5081555977

P-ISBN(Paperback): 9789535110873

P-ISBN(Hardback):  9789535110873

Subject： R394 medical genetics

Keyword： 医学遗传学

Language： ENG

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Chromatin Remodelling During Host-Bacterial Pathogen Interaction

Chapter

Chapter 8 Chromatin Remodelling During Host-Bacterial Pathogen Interaction

1. Introduction

2. Chromatin structure in transcription regulation

2.1. Histone modifications and transcription

2.2. Chromatin remodelling complex and transcription

3. The role of chromatin remodelling in the regulation of inflammatory gene expression

3.1. LPS-induced chromatin modification and target gene expression

3.2. Manipulation of host chromatin remodelling process by bacteria to facilitate infection

4. Chromatin remodeling and IFN-γ-induced transcriptional response

5. The potential role of HDAC inhibitors in treatment of infection

5.1. Inhibition of infection by targeting histone modifying enzymes in the pathogen

5.2. Effects of HDAC inhibitors on host defense against bacterial infection

6. Concluding remarks

Author details

References

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