De-Differentiation of Somatic Cells to a Pluripotent State ( Pluripotent Stem Cells )

Publication series ： Pluripotent Stem Cells

Author： Cristiane V. Wenceslau Irina Kerkis Nelson F. Lizier and AlexandreKerkis  

Publisher： IntechOpen‎

Publication year： 2013

E-ISBN: INT4591754372

P-ISBN(Paperback): 9789535111924

P-ISBN(Hardback):  9789535111924

Subject： Q2 Cytobiology

Keyword： 细胞生物学

Language： ENG

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De-Differentiation of Somatic Cells to a Pluripotent State

Chapter

Chapter 3 De-Differentiation of Somatic Cells to a Pluripotent State

1. Introduction

2. Natural in vivo pluripotent stem cell niches

2.1. Morula stem cell niche

2.2. Blastocyst stem cell niche

2.3. Epiblast stem cell niche: Naive and primed pluripotent stem cells

3. In vitro pluripotent stem cell niches

4. Generation of artificial pluripotent stem cell – Reprogramming strategies

4.1. Reprogramming by means of differentiated cells nuclear transfer

4.2. Reprogramming by means of stem cells nuclear transfer

4.3. Reprogramming by means of early embryonic environment

4.4. Reprogramming by means of cell fusion

4.5. Reprogramming by means of Yamanaka’s factors

5. Final considerations

Author details

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